Department of Otorhinolaryngology, Taiping Hospital, 34000 Taiping, Perak, Malaysia.
Department of Pathology, Taiping Hospital, 34000 Taiping, Perak, Malaysia.
Gulf J Oncolog. 2021 May;1(36):79-81.
Malignant transformation of recurrent respiratory papillomatosis (RRP) is a rare entity occurring in only less than 5% of patients with RRP. The risk of transformation can arise even in the absence of risk factors such as smoking and radiation. We describe a patient with juvenile RRP diagnosed since childhood, who suffered malignant transformation into a squamous cell carcinoma after 29 years. Keywords: Recurrent respiratory papillomatosis; laryngeal neoplasms; squamous cell carcinoma; human papilloma-virus.
复发性呼吸道乳头瘤病（RRP）的恶性转化是一种罕见的现象，仅发生在不到 5%的 RRP 患者中。即使没有吸烟和辐射等危险因素，也可能发生转化。我们描述了一位自童年起就被诊断为青少年 RRP 的患者，他在 29 年后恶性转化为鳞状细胞癌。关键词：复发性呼吸道乳头瘤病；喉肿瘤；鳞状细胞癌；人乳头瘤病毒。
