Department of Nephrology, Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran.
Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Saudi J Kidney Dis Transpl. 2021 Mar-Apr;32(2):579-583. doi: 10.4103/1319-2442.335475.
Kidney transplant recipients appear to be at increased risk for severe coronavirus disease 2019 (COVID-19) illness due to some factors such as comorbidities and chronic immunosuppression. Here, we report four cases of COVID-19 infection in kidney transplant recipients. The one case in this series with the high D-dimer levels and receiving tacrolimus had the worst outcome among reported patients. Other patients had better outcomes that probably due to the effect of immunosuppressive therapy in the prevention of COVID-19-induced cytokine storm. It was suggested that a high D-dimer level occurred in critical patients and likely prognostic and also, the immunosuppressive effect of some treatment regimens.
肾移植受者由于合并症和慢性免疫抑制等因素，似乎患严重 2019 冠状病毒病（COVID-19）的风险增加。在此，我们报告了 4 例肾移植受者 COVID-19 感染病例。在本系列中，有一例患者 D-二聚体水平较高且接受他克莫司治疗，其预后在报告的患者中最差。其他患者的预后较好，可能是由于免疫抑制治疗预防 COVID-19 引起的细胞因子风暴的作用。有研究表明，危急患者中出现高 D-二聚体水平可能具有预后意义，而某些治疗方案的免疫抑制作用也是如此。
