Machado David José de Barros, Ianhez Luiz Estevam
Hospital Alemão Oswaldo Cruz, São Paulo, Brazil.
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Transpl Infect Dis. 2020 Oct;22(5):e13306. doi: 10.1111/tid.13306. Epub 2020 May 26.
In late December 2019, China reported cases of respiratory illness in humans that involved a novel coronavirus SARS-CoV-2. On March 20, 2020, the first coronavirus disease 2019 (COVID-19) in Brazil was diagnosed, and by now, we present the report on the first case of COVID among transplant recipients in our country. A liver and kidney transplant patient with SARS-CoV-2 pneumonia without respiratory failure was treated in a clinical multimodal strategy consisting of symptomatic support therapy, immunosuppression reduction, use of anti-coronavirus drugs and heparin leading to a progressive improvement of patient symptoms till discharge. The authors also present a comprehensive review of published cases.
2019年12月下旬,中国报告了人类感染一种新型冠状病毒SARS-CoV-2的呼吸道疾病病例。2020年3月20日,巴西确诊首例2019冠状病毒病(COVID-19),截至目前,我们公布我国首例移植受者感染COVID的报告。一名患有SARS-CoV-2肺炎但无呼吸衰竭的肝肾移植患者,采用了包括对症支持治疗、减少免疫抑制、使用抗冠状病毒药物和肝素在内的临床多模式策略进行治疗,患者症状逐渐改善直至出院。作者还对已发表的病例进行了全面综述。