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Increased immune escape of the new SARS-CoV-2 variant of concern Omicron.

作者信息

Hu Jie, Peng Pai, Cao Xiaoxia, Wu Kang, Chen Juan, Wang Kai, Tang Ni, Huang Ai-Long

机构信息

Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Institute for Viral Hepatitis, Department of Infectious Diseases, the Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.

出版信息

Cell Mol Immunol. 2022 Feb;19(2):293-295. doi: 10.1038/s41423-021-00836-z. Epub 2022 Jan 11.

DOI:10.1038/s41423-021-00836-z
PMID:35017716
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8749347/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e14a/8803963/6efea1f3b09c/41423_2021_836_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e14a/8803963/6efea1f3b09c/41423_2021_836_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e14a/8803963/6efea1f3b09c/41423_2021_836_Fig1_HTML.jpg

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本文引用的文献

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Nature. 2022 Feb;602(7898):671-675. doi: 10.1038/s41586-021-04389-z. Epub 2021 Dec 23.
2
Striking antibody evasion manifested by the Omicron variant of SARS-CoV-2.奥密克戎变异株对 SARS-CoV-2 表现出明显的抗体逃逸。
Nature. 2022 Feb;602(7898):676-681. doi: 10.1038/s41586-021-04388-0. Epub 2021 Dec 23.
3
Antibody affinity maturation and cross-variant activity following SARS-CoV-2 mRNA vaccination: Impact of prior exposure and sex.
宿主内适应性和抗原性转变是影响严重急性呼吸综合征冠状病毒2(SARS-CoV-2)基因宿主内变异流行率的关键因素。
Viruses. 2025 Mar 2;17(3):362. doi: 10.3390/v17030362.
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The immune landscape and viral shedding of Omicron SARS-CoV-2 variants implicate immune escape.奥密克戎 SARS-CoV-2 变体的免疫格局和病毒脱落表明存在免疫逃逸。
Front Med (Lausanne). 2025 Jan 22;11:1478466. doi: 10.3389/fmed.2024.1478466. eCollection 2024.
5
Predictors of moderate, severe, and critical COVID-19 infection in a largely vaccinated kidney transplant recipient cohort during the Omicron era: the importance of timely booster vaccinations and early presentation to care.奥密克戎时代,在大部分接种疫苗的肾移植受者队列中,中度、重度和危重型新冠病毒感染的预测因素:及时接种加强针和尽早就诊的重要性
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SARS-CoV-2 mRNA 疫苗接种后的抗体亲和力成熟和跨变体活性:既往暴露和性别的影响。
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