Misra Puneet, Sharma Gautam, Tandon Nikhil, Kant Shashi, Sangral Meenu, Rai Sanjay K, Yadav Kapil, Vishnubhatla Sreenivas, Mandal Suprakash, Kardam Priyanka, Thakur Nishakar
Centre for Community Medicine, All India Institute of Medical Sciences, New Delhi, India.
Department of Cardiology, Centre for Integrative Medicine and Research, All India Institute of Medical Sciences, New Delhi, India.
Int J Yoga. 2021 Sep-Dec;14(3):222-228. doi: 10.4103/ijoy.ijoy_150_21. Epub 2021 Nov 22.
In view of the rising burden of type 2 diabetes mellitus (DM) cases in India, there is an urgent need for an effective, low-cost, sustainable intervention controlling diabetes thus preventing complications.
This study aimed to assess the effect of structured yoga programs on diabetes.
This was a community-based interventional study that was conducted in an urban resettlement colony of Delhi, India. Known diabetes patients with glycated hemoglobin (Hb1Ac) ≥6.5% were enrolled from 12 randomly selected blocks of the community with a sample size of 192 in each intervention and wait-listed control arm. The intervention was structured yoga of 50 min daily, 2 consecutive weeks in a nearby park and health center followed by twice a week home practice up to the 3 month. The primary outcome measure was HbA1c% and secondary outcome measures were lipid profile and fasting blood glucose.
Aper-protocol analysis was done. Mean, standard deviation (SD), and 95% confidence interval were estimated. The level of significance was considered for 0.05.
There was a significant decrease of Hb1Ac (0.5%, SD = 1.5, = 0.02), total cholesterol (11.7 mg/dl, SD = 40.5, < 0.01), and low-density lipoprotein (3.2 mg/dl, SD = 37.4, < 0.01) from baseline to end line in the intervention group. These changes in intervention group were also significantly different from the change in the wait-listed control group. The other variables did not change significantly.
It revealed that structured yoga program improved glycemic outcome and lipid profile of individuals in a community-based setting. Yoga can be a feasible strategy to control hyperglycemia, lipid levels, and can help better control type 2 DM.
鉴于印度2型糖尿病(DM)病例负担不断上升,迫切需要一种有效、低成本、可持续的干预措施来控制糖尿病,从而预防并发症。
本研究旨在评估结构化瑜伽项目对糖尿病的影响。
这是一项基于社区的干预性研究,在印度德里的一个城市安置区进行。从社区中随机选取的12个街区招募糖化血红蛋白(Hb1Ac)≥6.5%的已知糖尿病患者,每个干预组和候补对照组的样本量为192人。干预措施为在附近公园和健康中心每天进行50分钟的结构化瑜伽练习,连续两周,之后在家每周练习两次,持续3个月。主要结局指标为糖化血红蛋白百分比(HbA1c%),次要结局指标为血脂谱和空腹血糖。
进行了符合方案分析。估计了均值、标准差(SD)和95%置信区间。显著性水平设定为0.05。
干预组从基线到终点,糖化血红蛋白(降低0.5%,SD = 1.5,P = 0.02)、总胆固醇(降低11.7mg/dl,SD = 40.5,P < 0.01)和低密度脂蛋白(降低3.2mg/dl,SD = 37.4,P < 0.01)均有显著下降。干预组的这些变化也与候补对照组的变化有显著差异。其他变量无显著变化。
研究表明,在基于社区的环境中,结构化瑜伽项目改善了个体的血糖结局和血脂谱。瑜伽可以作为控制高血糖、血脂水平的可行策略,并有助于更好地控制2型糖尿病。