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颅骨放线菌病:一例罕见病例报告并文献复习

Cranial Mycetoma: A Rare Case Report with Review of Literature.

作者信息

Siraj Fouzia, Malik Akanksha, Shruti Sharma, Shankar K B, Singh Swati

机构信息

Department of Pathology, ICMR National Institute of Pathology, VMMC and Safdarjung Hospital, New Delhi, India.

Department of Neurosurgery, VMMC and Safdarjung Hospital, New Delhi, India.

出版信息

J Glob Infect Dis. 2021 Nov 23;13(4):192-195. doi: 10.4103/jgid.jgid_291_20. eCollection 2021 Oct-Dec.

Abstract

Mycetoma is a chronic granulomatous infection caused by fungi or bacteria, known as eumycetoma and actinomycetoma, respectively. Mycetoma commonly affects young males belonging to low socioeconomic strata, usually barefooted agricultural workers. It mainly affects lower and upper limbs presenting as a painless swelling with discharging sinus. Rarely, is it encountered in the intracranial location. The diagnosis relies on the clinical presentation and identification of the etiological agents within the tissue, by histology and special stains. It is important to specify the fungal or bacterial etiology, because the treatment of each is completely different. The management of such infections is challenging and should involve early diagnosis, the use of antibacterials or antifungals, and surgical removal of the lesion. To the best of our knowledge, only seven cases of intracranial mycetoma have been reported. The present case highlights the rarity of this lesion, thereby contributing to the existing literature and presenting its diagnostic implications.

摘要

足菌肿是一种由真菌或细菌引起的慢性肉芽肿性感染,分别称为真菌性足菌肿和放线菌性足菌肿。足菌肿通常影响社会经济地位较低的年轻男性,通常是赤脚的农业工人。它主要影响下肢和上肢,表现为无痛性肿胀并伴有引流窦道。颅内发生足菌肿的情况很少见。诊断依赖于临床表现以及通过组织学和特殊染色在组织内鉴定病原体。明确真菌或细菌病因很重要,因为二者的治疗方法完全不同。这类感染的治疗具有挑战性,应包括早期诊断、使用抗菌药物或抗真菌药物以及手术切除病变。据我们所知,仅报告过7例颅内足菌肿病例。本病例突出了这种病变的罕见性,从而为现有文献做出贡献并展示其诊断意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9143/8697824/8a7698e156cb/JGID-13-192-g001.jpg

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