Paramel Mohan Sunil, Ramalingam Murugan
Department of Oral and Maxillofacial Pathology, Sree Anjaneya Institute of Dental Sciences, Kozhikode, Kerala, India.
Department of Stems Cells and Regenerative Medicine, Malabar Medical College Hospital and Research Centre, Kozhikode, Kerala, India.
J Pharm Bioallied Sci. 2021 Nov;13(Suppl 2):S913-S916. doi: 10.4103/jpbs.jpbs_182_21. Epub 2021 Nov 10.
Peripheral nerve injury involves complex molecular, cellular, and genetic events that help in ultimate regeneration of nerve. Some key factors are upregulated and some downregulated in the process of regeneration of nerve to attain almost perfect architecture. This review renders short overview about how the injured neurons and supporting cells like Schwann cells help in creating ample microenvironment for regeneration of peripheral nerve and their maturation.
周围神经损伤涉及复杂的分子、细胞和遗传事件,这些事件有助于神经的最终再生。在神经再生过程中,一些关键因素上调,一些关键因素下调,以实现几乎完美的结构。这篇综述简要概述了受损神经元和施万细胞等支持细胞如何帮助为周围神经再生及其成熟创造充足的微环境。