Ambarwati Ambarwati, Sujono Tanti Azizah, Sintowati Retno
Department of Public Health, Faculty of Health Sciences, Universitas Muhammadiyah Surakarta, Surakarta, Indonesia.
Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Muhammadiyah Surakarta, Surakarta, Indonesia.
J Pharm Bioallied Sci. 2021 Nov;13(Suppl 2):S1369-S1374. doi: 10.4103/jpbs.jpbs_205_21. Epub 2021 Nov 10.
The study aimed to determine the inhibition activity of a combination of Noni fruit extract and Pandan leaves extract toward bacterial isolates that cause dandruff and to determine the potential of extract combination as an anti-dandruff shampoo.
The test bacteria were isolated from dandruff. The inhibition test of the extract combination was done by paper disc and well diffusion method. The identification of bacterial isolates was done in Balai Laboratorium Kesehatan Yogyakarta.
The study showed that the density of bacteria isolated from dandruff was 3.4 × 10 CFU/g. There were 28 pure bacteria isolates from purification process. The combination of Noni and Pandan extracts (1:1 v/v) could inhibit the growth of 92.9% bacterial isolates. There were seven species of bacteria from a total of 28 pure isolates, namely: sp, sp, and sp.
Based on the research, it can be concluded that a combination of Noni fruit extract and Pandan leaves extract inhibited the growth of bacteria isolated from dandruff, so the combination of the extracts has potential as an anti-dandruff shampoo.
本研究旨在确定诺丽果提取物和露兜树叶提取物组合对引起头皮屑的细菌分离株的抑制活性,并确定提取物组合作为去屑洗发水的潜力。
测试细菌从头皮屑中分离得到。提取物组合的抑制试验采用纸片法和打孔扩散法进行。细菌分离株的鉴定在日惹卫生实验室进行。
研究表明,从头皮屑中分离出的细菌密度为3.4×10 CFU/g。纯化过程中有28株纯细菌分离株。诺丽和露兜树提取物(1:1 v/v)的组合可抑制92.9%的细菌分离株生长。28株纯分离株中共有7种细菌,分别为: 菌、 菌和 菌。
基于本研究,可以得出结论,诺丽果提取物和露兜树叶提取物的组合抑制了从头皮屑中分离出的细菌的生长,因此该提取物组合有潜力作为去屑洗发水。