Vilardaga Jennifer C Plumb, Kelleher Sarah, Diachina Allison, Riley Jennie, Somers Tamara
Duke University Health System.
Duke University School of Medicine.
Res Sq. 2022 Jan 3:rs.3.rs-1182374. doi: 10.21203/rs.3.rs-1182374/v1.
Background Osteoarthritis (OA) pain is common and leads to functional impairment for many older adults. Physical activity can improve OA outcomes for older adults, but few are appropriately active. Behavioral interventions can reduce barriers to physical activity. We developed and tested a brief, novel behavioral intervention for older adults combining values to enhance motivation and strategic activity pacing to improve arthritis-related pain and functioning and increase physical activity. Methods A randomized feasibility and acceptability pilot trial compared Engage-PA to treatment as usual plus fitness tracker (TAU+) in N=40 adults age 65+ with OA pain in the knee or hip. Engage-PA involved two 60-minute telephone sessions. All participants wore a fitness tracker to collect daily steps throughout the study and completed baseline and post-treatment assessments of secondary outcomes (arthritis-related pain and physical functioning, physical activity, psychological distress, psychological flexibility, and value-guided action). The impact of COVID-19 on general wellbeing and physical activity was also assessed. Descriptive statistics were conducted for feasibility and acceptability outcomes. Indicators of improvement in secondary outcomes were examined via change scores from baseline to post-treatment and performing independent samples -tests to assess for between-group differences. Results Feasibility was high; 100% accrual, low (5%) attrition, and 100% completion of study sessions. Acceptability was high, with 89% finding the intervention "mostly" or "very" helpful. Engage-PA participants demonstrated improvements in arthritis pain severity ( =1.68, <.05), arthritis-related physical functioning ( =.875, =.056), and self-reported activity ( =.875, <.05) from baseline to post-treatment as compared to TAU+. Sixty-three percent of participants provided useable objective daily steps data. Other secondary outcome patterns were not interpretable in this small sample. COVID-19 added additional burden to participants, such that 50% were exercising less, 68% were more sedentary, and 72% lost access to spaces and social support to be active. Conclusions Engage-PA is a promising brief, novel behavioral intervention that has potential to support older adults in improving arthritis-related pain and functioning and increasing physical activity. The feasibility and acceptability of the intervention is particularly notable as most participants reported COVID-19 added more barriers to physical activity, and Engage-PA may be appealing in future studies. Trial Registration: clinicaltrials.gov, NCT04490395, registered 7/29/2020, https://clinicaltrials.gov/ct2/show/NCT04490395.
骨关节炎(OA)疼痛很常见,会导致许多老年人出现功能障碍。体育活动可以改善老年人的骨关节炎预后,但很少有人进行适当的运动。行为干预可以减少体育活动的障碍。我们开发并测试了一种针对老年人的简短、新颖的行为干预措施,该措施结合价值观以增强动机,并采用策略性活动节奏来改善与关节炎相关的疼痛和功能,并增加体育活动。方法:一项随机可行性和可接受性试点试验将Engage-PA与常规治疗加健身追踪器(TAU+)进行了比较,研究对象为40名65岁及以上患有膝部或髋部OA疼痛的成年人。Engage-PA包括两次60分钟的电话会议。所有参与者在整个研究过程中都佩戴健身追踪器以收集每日步数,并完成次要结局(与关节炎相关的疼痛和身体功能、体育活动、心理困扰、心理灵活性和价值导向行动)的基线和治疗后评估。还评估了COVID-19对总体幸福感和体育活动的影响。对可行性和可接受性结局进行了描述性统计。通过从基线到治疗后的变化分数以及进行独立样本t检验来评估组间差异,从而检查次要结局的改善指标。结果:可行性很高;招募率为100%,损耗率很低(5%),研究会议的完成率为100%。可接受性很高,89%的人认为该干预措施“非常”或“极其”有帮助。与TAU+相比,Engage-PA参与者从基线到治疗后在关节炎疼痛严重程度(t=1.68,P<.05)、与关节炎相关的身体功能(t=.875,P=.056)和自我报告的活动(t=.875,P<.05)方面均有改善。63%的参与者提供了可用的每日客观步数数据。在这个小样本中,其他次要结局模式无法解释。COVID-19给参与者增加了额外负担,50%的人运动量减少,68%的人久坐时间增加,72%的人失去了进行活动的空间和社会支持。结论:Engage-PA是一种很有前景的简短、新颖的行为干预措施,有可能帮助老年人改善与关节炎相关的疼痛和功能,并增加体育活动。该干预措施的可行性和可接受性尤其值得注意,因为大多数参与者报告COVID-19给体育活动增加了更多障碍,而Engage-PA在未来的研究中可能具有吸引力。试验注册:clinicaltrials.gov,NCT04490395,于2020年7月29日注册,https://clinicaltrials.gov/ct2/show/NCT04490395 。