CNR-Institute of Biomolecular Chemistry, 95126 Catania, Italy.
CNR-Institute of Crystallography, 95126 Catania, Italy.
Chem Commun (Camb). 2022 Mar 3;58(19):3126-3129. doi: 10.1039/d1cc06530k.
Luminescent and photothermic carbon polymer dots (CPDs-PNM), composed of a carbonized core and cross-linked chains of poly(-isopropylacrylamide), were synthetized by a novel, simple, solvent- and reagent-free method. The formation of CPDs-PNM was controlled by both temperature and heating time. The CPDs-PNM exhibited LCST behaviour, high photothermal conversion efficiency, curcumin loading capacity and no toxicity to eukaryotic cells. Proof of concept experiments confirmed an excellent thermally induced drug release activity to be used for photothermally controlled drug release.
发光和光热碳聚合物点（CPD-PNM）由碳化核和交联的聚（异丙基丙烯酰胺）链组成，通过一种新颖、简单、无溶剂和无试剂的方法合成。CPD-PNM 的形成受温度和加热时间的控制。CPD-PNM 表现出 LCST 行为、高光热转换效率、姜黄素负载能力和对真核细胞无毒。概念验证实验证实了优异的热诱导药物释放活性，可用于光热控制药物释放。
