1 型糖尿病诊断后一年内开始进行连续血糖监测与改善血糖结局相关：7 年随访研究。
Continuous Glucose Monitoring Initiation Within First Year of Type 1 Diabetes Diagnosis Is Associated With Improved Glycemic Outcomes: 7-Year Follow-Up Study.
出版信息
Diabetes Care. 2022 Mar 1;45(3):750-753. doi: 10.2337/dc21-2004.
OBJECTIVE
To evaluate long-term glycemic outcomes of continuous glucose monitoring (CGM) initiation within the first year of type 1 diabetes diagnosis.
RESEARCH DESIGN AND METHODS
Patients with type 1 diabetes (N = 396) were divided into three groups: 1) CGM (CGM use within 1 year of diabetes diagnosis and continued through the study), 2) no-CGM (no CGM use throughout the study), and 3) new-CGM (CGM use after 3 years since diabetes diagnosis). Patients were followed up to 7 years.
RESULTS
A1c was significantly lower in the CGM compared with the no-CGM group throughout 7 years of follow-up (least squares mean A1c values: 6 months, 7.3% vs. 8.1%; 1 year, 7.4% vs. 8.6%; 2 years, 7.7% vs. 9.1%; 3 years, 7.6% vs. 9.3%; 4 years, 7.4% vs. 9.6%; 5 years, 7.6% vs. 9.7%; 6 years, 7.5% vs. 10.0%; and 7 years, 7.6% vs. 9.8%; for all, P < 0.001) adjusting for age at diagnosis, sex, and insulin delivery method.
CONCLUSIONS
CGM initiation within first year of type 1 diabetes diagnosis results in long-term improvement in A1c.
目的
评估 1 型糖尿病诊断后第一年开始连续血糖监测（CGM）的长期血糖结果。
研究设计与方法
将 396 名 1 型糖尿病患者分为三组：1）CGM（CGM 在糖尿病诊断后 1 年内使用，并在研究期间持续使用），2）无 CGM（整个研究期间不使用 CGM），3）新 CGM（糖尿病诊断后 3 年后使用 CGM）。患者随访 7 年。
结果
在 7 年的随访中，CGM 组的 A1c 明显低于无 CGM 组（最小二乘均值 A1c 值：6 个月，7.3%比 8.1%；1 年，7.4%比 8.6%；2 年，7.7%比 9.1%；3 年，7.6%比 9.3%；4 年，7.4%比 9.6%；5 年，7.6%比 9.7%；6 年，7.5%比 10.0%；7 年，7.6%比 9.8%；所有组，P<0.001），调整了诊断时的年龄、性别和胰岛素输送方法。
结论
1 型糖尿病诊断后第一年开始 CGM 可长期改善 A1c。
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