Department of Epidemiology, Milken Institute School of Public Health at the George Washington University, District of Columbia, USA.
Community Education Group, Inc., District of Columbia, USA.
AIDS Res Hum Retroviruses. 2022 Aug;38(8):631-644. doi: 10.1089/AID.2021.0127. Epub 2022 Feb 21.
HIV is experienced across diverse populations, with gender and racial/ethnic minority populations bearing a significant proportion of disease. With National Institutes of Health (NIH) placing a priority on the enrollment of women and racial/ethnic minorities into studies, it is important to understand the diversity of participants in research. We sought to characterize how HIV cure research studies report data on diversity. A sampling frame of publications with funding provided by the Martin Delaney Collaboratories for HIV Research in 2019 was reviewed for reporting of demographic data. Of 55 publications that included research on humans/human specimens, only 51% provided any demographic description. There often is insufficient consideration of diversity of populations in HIV cure research. Ameliorating gaps in this regard will require recruitment of diverse populations/specimens and specifications to report demographic data in articles. This will ensure inclusion of diverse participants in HIV cure research from earliest laboratory to eventual phase III studies.
艾滋病毒影响着不同人群，其中性别和少数族裔人群承担着相当大比例的疾病负担。美国国立卫生研究院 (NIH) 将重点放在将女性和少数族裔纳入研究中，因此了解研究参与者的多样性非常重要。我们试图描述艾滋病毒治愈研究报告多样性数据的方式。对 2019 年马丁·德莱尼艾滋病毒研究合作体资助的出版物抽样框架进行了审查，以报告人口统计数据。在包含人类/人类标本研究的 55 篇出版物中，只有 51%提供了任何人口统计描述。在艾滋病毒治愈研究中，往往没有充分考虑人群的多样性。要弥补这方面的差距，需要招募不同的人群/标本，并规定在文章中报告人口统计数据。这将确保从最早的实验室到最终的 III 期研究，将不同的参与者纳入艾滋病毒治愈研究中。
