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单中心经验:超高密度标测指导下的局灶性房性心动过速导管消融。

Single-center experience of ultra-high-density mapping guided catheter ablation of focal atrial tachycardia.

机构信息

Department of Medicine I, University Hospital Munich, Ludwig Maximilians University, Munich, Germany.

German Cardiovascular Research Centre (DZHK), partner site: Munich Heart Alliance, Munich, Germany.

出版信息

Clin Cardiol. 2022 Mar;45(3):291-298. doi: 10.1002/clc.23774. Epub 2022 Jan 12.

DOI:10.1002/clc.23774
PMID:35019172
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8922533/
Abstract

INTRODUCTION

Catheter ablation is the treatment of choice for recurrent focal atrial tachycardia (FAT) as medical therapy is limited. Routinely, a three-dimensional mapping system is used. Whether or not optimized signal detection does improve ablation success rates has not yet been investigated. This retrospective cohort study compared ablation procedures using an ultra-high-density mapping system (UHDM, Rhythmia, Boston Scientific) with improved signal detection and automatic annotation with procedures using a conventional electroanatomic mapping system (CEAM, Biosense Webster, CARTO).

METHODS

All patients undergoing ablation for FAT using UHDM or CEAM from April 2015 to August 2018 were included. Endpoints comprised procedural parameters, acute success as well as freedom from arrhythmia 12 months after ablation.

RESULTS

A total of 70 patients underwent ablation (48 with UHDM, 22 with CEAM). No significant differences were noted for parameters like procedural and radiation duration, area dose, and RF applications. Acute success was significantly higher in the UHDM cohort (89.6% vs. 68.2%, p = .03). Nevertheless, arrhythmia freedom 12 months after ablation was almost identical (56.8% vs. 60%, p = .87), as more patients with acute success of ablation presented with a relapse during follow-up (35.0 vs. 7.7%, p = .05).

CONCLUSION

Acute success rate of FAT ablation might be improved by UHDM, without an adverse effect on procedural parameters. Nevertheless, further research is needed to understand the underlying mechanism for increased recurrence rates after acute successful ablation.

摘要

简介

导管消融是复发性局灶性房性心动过速(FAT)的首选治疗方法,因为药物治疗效果有限。通常,使用三维标测系统。优化信号检测是否确实能提高消融成功率尚未得到研究。这项回顾性队列研究比较了使用超高密度标测系统(UHDM,波士顿科学公司的 Rhythmia)进行的消融程序,该系统具有改进的信号检测和自动注释功能,以及使用传统电生理标测系统(CEAM,Biosense Webster,CARTO)进行的消融程序。

方法

纳入 2015 年 4 月至 2018 年 8 月期间使用 UHDM 或 CEAM 进行 FAT 消融的所有患者。终点包括手术参数、即刻成功率以及消融 12 个月后的心律失常无复发率。

结果

共 70 例患者接受消融(UHDM 组 48 例,CEAM 组 22 例)。手术时间和辐射时间、面积剂量和 RF 应用等参数无显著差异。UHDM 组即刻成功率显著更高(89.6% vs. 68.2%,p=0.03)。然而,消融 12 个月后的心律失常无复发率几乎相同(56.8% vs. 60%,p=0.87),因为更多急性成功的消融患者在随访期间出现复发(35.0% vs. 7.7%,p=0.05)。

结论

UHDM 可能提高 FAT 消融的即刻成功率,而不会对手术参数产生不利影响。然而,需要进一步研究以了解急性成功消融后复发率增加的潜在机制。

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