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使用新型卷积神经网络模型从基于纸张的心电图迹线图像数据中诊断 COVID-19 疾病。

COVID-19 disease diagnosis from paper-based ECG trace image data using a novel convolutional neural network model.

机构信息

Electrical-Electronics Engineering Department, Alanya Alaaddin Keykubat University, 07425, Alanya, Antalya, Turkey.

出版信息

Phys Eng Sci Med. 2022 Mar;45(1):167-179. doi: 10.1007/s13246-022-01102-w. Epub 2022 Jan 12.

Abstract

Clinical reports show that COVID-19 disease has impacts on the cardiovascular system in addition to the respiratory system. Available COVID-19 diagnostic methods have been shown to have limitations. In addition to current diagnostic methods such as low-sensitivity standard RT-PCR tests and expensive medical imaging devices, the development of alternative methods for the diagnosis of COVID-19 disease would be beneficial for control of the COVID-19 pandemic. Further, it is important to quickly and accurately detect abnormalities caused by COVID-19 on the cardiovascular system via ECG. In this study, the diagnosis of COVID-19 disease is proposed using a novel deep Convolutional Neural Network model by using only ECG trace images created from ECG signals of COVID-19 infected patients based on the abnormalities caused by the COVID-19 virus on the cardiovascular system. An overall classification accuracy of 98.57%, 93.20%, 96.74% and AUC value of 0.9966, 0.9771, 0.9905 is achieved for COVID-19 vs. Normal, COVID-19 vs. Abnormal Heartbeats, COVID-19 vs. Myocardial Infarction binary classification tasks, respectively. In addition, an overall classification accuracy of 86.55% and 83.05% is achieved for COVID-19 vs. Abnormal Heartbeats vs. Myocardial Infarction and Normal vs. COVID-19 vs. Abnormal Heartbeats vs. Myocardial Infarction multi-classification tasks. This study is believed to have great potential to speed up the diagnosis and treatment of COVID-19 patients, saving clinicians time and facilitating the control of the pandemic.

摘要

临床报告表明,COVID-19 疾病除了呼吸系统之外,还会对心血管系统造成影响。现有的 COVID-19 诊断方法已经显示出其局限性。除了目前的诊断方法,如低灵敏度的标准 RT-PCR 测试和昂贵的医疗成像设备外,开发 COVID-19 疾病的替代诊断方法将有助于控制 COVID-19 大流行。此外,通过心电图快速准确地检测 COVID-19 对心血管系统引起的异常也很重要。在这项研究中,我们提出了一种新的深度卷积神经网络模型,仅使用基于 COVID-19 病毒对心血管系统引起的异常的从 COVID-19 感染者的心电图信号创建的心电图迹线图像来诊断 COVID-19 疾病。对于 COVID-19 与正常、COVID-19 与异常心跳、COVID-19 与心肌梗死的二进制分类任务,分别实现了 98.57%、93.20%、96.74%的整体分类准确率和 0.9966、0.9771、0.9905 的 AUC 值。此外,对于 COVID-19 与异常心跳与心肌梗死、正常与 COVID-19 与异常心跳与心肌梗死的多分类任务,分别实现了 86.55%和 83.05%的整体分类准确率。这项研究有望大大加快 COVID-19 患者的诊断和治疗速度,为临床医生节省时间,并有助于控制大流行。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d4a/8753334/ebb6d58d7486/13246_2022_1102_Fig1_HTML.jpg

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