Adams Christopher D, Brunetti Luigi, Davidov Liza, Mujia Jose, Rodricks Michael
Robert Wood Johnson University Hospital Somerset, Somerville, NJ, USA.
Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ, USA.
SAGE Open Med. 2022 Jan 7;10:20503121211066471. doi: 10.1177/20503121211066471. eCollection 2022.
A high-intensity staffing model has been defined as either mandatory intensivist consultation or a closed intensive care unit in which intensivists manage all aspects of patient care. In the current climate of limited healthcare resources, transitioning to a closed intensive care unit model may lead to significant improvements in patient care and resource utilization.
This is a single-center, retrospective cohort study of all mechanically ventilated intensive care unit admissions in the pre-intensive care unit closure period of 1 October 2014 to 30 September 2015 as compared with the post-intensive care unit closure period of 1 November 2015 to 31 October 2016. Patient demographics as well as outcome data (duration of mechanical ventilation, length of stay, direct costs, complications, and mortality) were abstracted from the electronic health record. All data were analyzed using descriptive and inferential statistics. Regression analyses were used to adjust outcomes for potential confounders.
A total of 549 mechanically ventilated patients were included in our analysis: 285 patients in the pre-closure cohort and 264 patients in the post-closure cohort. After adjusting for confounders, there was no significant difference in mortality rates between the pre-closure (40.7%) and post-closure (38.6%) groups (adjusted odds ratio = 0.82; 95% confidence interval = 0.56-1.18; = 0.283). The post-closure cohort was found to have significant reductions in duration of mechanical ventilation (3.71-1.50 days; < 0.01), intensive care unit length of stay (5.8-2.7 days; < 0.01), hospital length of stay (10.9-7.3 days; < 0.01), and direct hospital costs (US $16,197-US $12,731; = 0.009). Patient complications were also significantly reduced post-intensive care unit closure.
Although a closed intensive care unit model in our analysis did not lead to a statistical difference in mortality, it did demonstrate multiple beneficial outcomes including reduced ventilator duration, decreased intensive care unit and hospital length of stay, fewer patient complications, and reduced direct hospital costs.
高强度人员配置模式被定义为强制重症医学专家会诊或设立封闭式重症监护病房,由重症医学专家管理患者护理的各个方面。在当前医疗资源有限的情况下,向封闭式重症监护病房模式转变可能会显著改善患者护理和资源利用情况。
这是一项单中心回顾性队列研究,对比了2014年10月1日至2015年9月30日重症监护病房关闭前期间与2015年11月1日至2016年10月31日重症监护病房关闭后期间所有接受机械通气的重症监护病房入院患者。从电子健康记录中提取患者人口统计学数据以及结局数据(机械通气持续时间、住院时间、直接费用、并发症和死亡率)。所有数据均使用描述性和推断性统计进行分析。回归分析用于调整潜在混杂因素对结局的影响。
我们的分析共纳入549例接受机械通气的患者:关闭前队列中有285例患者,关闭后队列中有264例患者。在调整混杂因素后,关闭前组(40.7%)和关闭后组(38.6%)的死亡率无显著差异(调整后的比值比 = 0.82;95%置信区间 = 0.56 - 1.18;P = 0.283)。结果发现,关闭后队列的机械通气持续时间显著缩短(从3.71天降至1.50天;P < 0.01),重症监护病房住院时间缩短(从5.8天降至2.7天;P < 0.01),医院住院时间缩短(从10.9天降至7.3天;P < 0.01),医院直接费用降低(从16,197美元降至12,731美元;P = 0.009)。重症监护病房关闭后患者并发症也显著减少。
尽管在我们的分析中,封闭式重症监护病房模式并未导致死亡率出现统计学差异,但它确实显示出多种有益结局,包括机械通气持续时间缩短、重症监护病房和医院住院时间减少、患者并发症减少以及医院直接费用降低。