Poudel Ishan
Pediatrics, Woodhull Medical Center, Brooklyn, USA.
Cureus. 2021 Dec 11;13(12):e20350. doi: 10.7759/cureus.20350. eCollection 2021 Dec.
Infantile hypertrophic pyloric stenosis (IHPS) is a disorder encountered in infancy that is caused by hypertrophy of the musculature of the pylorus of the stomach. It may present as partial or complete gastric outlet obstruction. Multiple previous literatures have discussed the incidences and variability in the presentation of IHPS. However, there are very few reports of IHPS occurring in dizygotic twins, especially dizygotic twins of different sexes. Here we present a very rare case of dizygotic twins (a male and a female) affected with IHPS. With this study, we aim to identify the factors that lead to variability in severity and onset of symptoms in dizygotic twins of the opposite sex. We also aim to pay special attention to the etiology and mechanism of development of IHPS in dizygotic twins of the opposite sex.
婴儿肥厚性幽门狭窄(IHPS)是一种在婴儿期出现的疾病,由胃幽门肌肉组织肥大引起。它可能表现为部分或完全性胃出口梗阻。之前有多项文献讨论了IHPS的发病率及表现的变异性。然而,关于双卵双胞胎发生IHPS的报道非常少,尤其是不同性别的双卵双胞胎。在此,我们报告一例非常罕见的双卵双胞胎(一男一女)患IHPS的病例。通过本研究,我们旨在确定导致异性双卵双胞胎症状严重程度和发作变异性的因素。我们还旨在特别关注异性双卵双胞胎中IHPS的病因及发病机制。