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口腔和颅面疾病中的细胞外囊泡:从基础知识到临床视角。

Extracellular Vesicles in Oral and Craniofacial Diseases: from Basic Knowledge to Clinical Perspectives.

出版信息

Chin J Dent Res. 2021 Dec 23;24(4):213-217. doi: 10.3290/j.cjdr.b2440527.

Abstract

Extracellular vesicles (EVs), produced by exocytosis or membrane budding of cells, are membranous vesicles that carry specific proteins, nucleic acids and other bioactive molecules. EVs are indispensable carriers of biological information and play a critical role in cell-to-cell communication. Due to their involvement in physiological and pathological processes, EVs have shown great potential in the diagnosis and treatment of various diseases in recent years. The present review focuses on the regulatory role of EVs in oral and craniofacial diseases to provide valuable insights into possible applications in translational medicine.

摘要

细胞通过胞吐或膜出芽产生的细胞外囊泡(EVs)是一种携带特定蛋白质、核酸和其他生物活性分子的膜性囊泡。EVs 是生物信息的不可或缺的载体,在细胞间通讯中发挥着关键作用。由于它们参与生理和病理过程,EVs 在近年来各种疾病的诊断和治疗中显示出巨大的潜力。本综述重点介绍 EVs 在口腔和颅面疾病中的调控作用,为转化医学中的可能应用提供有价值的见解。

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