Integrated Brain Health Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.
Harvard Medical School, Boston, MA, USA; Partners MS Center at Brigham and Women's Hospital, Boston, MA, USA.
Mult Scler Relat Disord. 2022 Feb;58:103493. doi: 10.1016/j.msard.2022.103493. Epub 2022 Jan 4.
Timely personalized medicine is an unmet, critical need in multiple sclerosis (MS). A major barrier to providing individualized care is the lack of information on which interventions are most appropriate for whom. In this viewpoint, we submit a rationale and three-step roadmap to personalized integrative medicine. This multidisciplinary team approach requires that we (1) comprehensively assess whole health at diagnosis, (2) appropriately integrate data within electronic health record systems and leverage machine learning to analyze big data, and (3) design, test, and deliver multimodal interventions. Using a whole-person approach to assessment and intervention, we will be better informed to provide personalized care at the level of the individual.
及时的个性化医学是多发性硬化症（MS）未满足的关键需求。提供个性化护理的主要障碍是缺乏关于哪些干预措施最适合谁的信息。在本观点中，我们提出了个性化整合医学的基本原理和三步路线图。这种多学科团队方法要求我们（1）在诊断时全面评估整体健康，（2）在电子健康记录系统中适当整合数据并利用机器学习分析大数据，以及（3）设计、测试和提供多种模式的干预措施。通过采用整体方法进行评估和干预，我们将更好地了解如何在个体层面提供个性化护理。
