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一例以癫痫发作为首发症状的原发性不明的中枢神经系统转移性黑色素瘤病例。

A Case of Metastatic CNS Melanoma of Unknown Primary Presenting with Seizures.

作者信息

Nguyen Viva, Aboulenain Samar, Mohammed Shawn, Perez Parra Sahyli

机构信息

Internal Medicine Resident, University of Miami JFK GME, Atlantis, FL, USA.

Medical Specialists of the Palm Beaches Neurology, JFK Medical Center, Atlantis, FL, USA.

出版信息

Case Rep Med. 2022 Jan 6;2022:3099750. doi: 10.1155/2022/3099750. eCollection 2022.

Abstract

Seizures are a common occurrence. The goal of evaluating a seizure is to identify the etiology and to determine the likelihood of recurrence as well as guide management. We present a unique presentation of a 47-year-old female that presented with late onset seizures admitted due to status epilepticus. Brain magnetic resonance indicated diffuse supratentorial hemorrhagic lesions. Neurological workup including brain vessel imaging, CT chest, abdomen, and pelvis as well as CSF and serological workup for vasculitis failed to demonstrate the cause of her brain lesions. Ultimately, a brain biopsy showed metastatic melanoma of unknown primary origin.

摘要

癫痫发作很常见。评估癫痫发作的目的是确定病因、判断复发可能性并指导治疗。我们报告了一例独特病例,一名47岁女性因癫痫持续状态入院,出现迟发性癫痫发作。脑部磁共振成像显示幕上弥漫性出血性病变。包括脑血管成像、胸部、腹部和骨盆CT以及针对血管炎的脑脊液和血清学检查在内的神经学检查均未能明确其脑部病变的原因。最终,脑活检显示为原发灶不明的转移性黑色素瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b58f/8758325/cd988726c12d/CRIM2022-3099750.001.jpg

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