Batool Razia, Riaz Noreen, Junaid Hafiz Muhammad, Waseem Muhammad Tahir, Khan Zulfiqar Ali, Nawazish Shamyla, Farooq Umar, Yu Cong, Shahzad Sohail Anjum
Department of Chemistry, COMSATS University Islamabad, Abbottabad Campus, Abbottabad 22060, Pakistan.
Department of Chemistry, Government College University, Faisalabad 38000, Pakistan.
ACS Omega. 2021 Dec 28;7(1):1057-1070. doi: 10.1021/acsomega.1c05644. eCollection 2022 Jan 11.
Nitroaromatic explosives are a class of compounds that are responsible for various health hazards and terrorist outrages. Among these, sensitive detection of 2,4,6-trinitrophenol (TNP) explosive has always been highly desirable considering public health and national security. In this regard, three fluorene-based conjugated polymers (, , and ) were synthesized through the Suzuki-Miyaura coupling reaction and were found to be highly sensitive for fluorescence detection of TNP with detection limits of 3.2, 5.7, and 6.1 pM, respectively. Excellent selectivity of CPs toward TNP was attributed to their unique π-π interactions based on fluorescence studies and density functional theory (DFT) calculations. The high sensitivity of CPs to TNP was attributed to the static quenching mechanism based on the photoinduced electron transfer process and was evaluated by fluorescence, UV-visible absorption, dynamic light scattering, Job's plots, the Benesi-Hildebrand plots, and DFT calculations. CPs were also used for colorimetric and real-water sample analysis for the detection of TNP explosive. Meanwhile, sensor-coated test strips were fabricated for on-site detection of TNP, which makes them convenient solid-supported sensors.
硝基芳香族炸药是一类会造成各种健康危害和恐怖袭击事件的化合物。其中，考虑到公众健康和国家安全，对2,4,6-三硝基苯酚（TNP）炸药进行灵敏检测一直是非常必要的。在这方面，通过铃木-宫浦偶联反应合成了三种芴基共轭聚合物（、和），发现它们对TNP的荧光检测具有高灵敏度，检测限分别为3.2、5.7和6.1 pM。基于荧光研究和密度泛函理论（DFT）计算，共轭聚合物对TNP具有优异的选择性归因于其独特的π-π相互作用。共轭聚合物对TNP的高灵敏度归因于基于光致电子转移过程的静态猝灭机制，并通过荧光、紫外-可见吸收、动态光散射、乔布图、贝内西-希尔德布兰德图和DFT计算进行了评估。共轭聚合物还用于比色法和实际水样分析以检测TNP炸药。同时，制备了传感器涂层测试条用于TNP的现场检测，这使其成为方便的固体支撑传感器。
