Department of Chemistry, COMSATS University Islamabad, Abbottabad Campus, Abbottabad 22060, Pakistan.
Department of Chemistry, Government College University, Faisalabad 38000, Pakistan.
Spectrochim Acta A Mol Biomol Spectrosc. 2022 May 5;272:120994. doi: 10.1016/j.saa.2022.120994. Epub 2022 Feb 9.
Rapid detection of 2,4,6-trinitrophenol (TNP) in real samples has recently attained considerable attention from the perspective of national security, human health, and environmental safety. In this context, cost-effective and convenient detection of TNP explosive was accomplished through two new fluorescein based sensors F2 and F3. Sensors displayed effective fluorescence quenching response towards TNP in the aqueous medium. Highly sensitive fluorescence detection of TNP explosive (detection limit, 0.73 (F2) and 1.7 nM (F3)) was governed by ground-state charge transfer complex formation, facilitated by favorable H-bonding between sensor and TNP explosive. Fluorescence quenching mechanism for the detection of TNP explosive was investigated through UV-Visible absorption, dynamic light scattering (DLS), density functional theory (DFT) calculations, the Benesi-Hildebrand, and Job's plots. Advantageously, sensors displayed selective and immediate colorimetric recognition of TNP explosive. Importantly, sensors exhibited quick response time towards TNP even in the presence of potential interferences that make them highly suitable for practical applications. Sensors were successfully applied for fluorescent and colorimetric detection of TNP explosive in industrial water samples and fabrication of logic gates. Further, convenient contact mode and instant surface sensing of TNP explosive were achieved through the fabrication of fluorescent strips and explosive responsive test kits.
近年来，从国家安全、人类健康和环境安全的角度出发，人们对 2,4,6-三硝基苯酚（TNP）的快速检测引起了相当大的关注。在这种情况下，通过两种新的基于荧光素的传感器 F2 和 F3 实现了对 TNP 爆炸物的经济高效且方便的检测。传感器在水介质中对 TNP 表现出有效的荧光猝灭响应。TNP 爆炸物的高灵敏度荧光检测（检测限，0.73（F2）和 1.7 nM（F3））由基态电荷转移配合物形成控制，传感器和 TNP 爆炸物之间的有利氢键促进了这种形成。通过紫外-可见吸收、动态光散射（DLS）、密度泛函理论（DFT）计算、本内希勒布兰德（Benesi-Hildebrand）和乔布（Job）图谱研究了用于检测 TNP 爆炸物的荧光猝灭机制。有利的是，传感器对 TNP 爆炸物表现出选择性和即时比色识别。重要的是，即使存在潜在干扰，传感器对 TNP 的响应时间也很快，这使其非常适合实际应用。传感器成功地用于工业水样中的 TNP 爆炸物的荧光和比色检测以及逻辑门的制作。此外，通过制造荧光条和爆炸物响应测试套件，实现了 TNP 爆炸物的方便接触模式和即时表面传感。
