Murray T J
Can Med Assoc J. 1978 Jun 10;118(11):1407-10.
Tourette's syndrome, or Gilles de la Tourette's disease, is a disorder characterized by involuntary tic-like muscular movements, compulsive behaviour and involuntary vocalization of sounds, words or profanities. It begins in childhood and may persist for life, with a varied pattern and course. Recent studies indicate an organic basis for the disorder, and an abnormality of dopamine or purine metabolism has been suggested. The treatment of choice is haloperidol administration; most patients do well with low or moderate doses for long periods. Because these patients are often mistakenly regarded as anxious, psychoneurotic or hysterical, correct diagnosis is important if they are to be treated appropriately and regarded properly in the home, school and society.
图雷特氏综合征，或称为 Gilles de la Tourette 病，是一种以不自主的抽搐样肌肉运动、强迫行为以及不自主地发出声音、词语或脏话为特征的疾病。它始于童年时期，可能会持续终生，表现形式和病程各不相同。最近的研究表明该疾病存在器质性基础，有人提出多巴胺或嘌呤代谢异常与之有关。首选治疗方法是服用氟哌啶醇；大多数患者长期使用低剂量或中等剂量就能取得良好效果。由于这些患者常常被错误地认为是焦虑、精神神经症或癔症患者，因此如果要对他们进行恰当治疗，并在家庭、学校和社会中得到正确对待，正确诊断就很重要。
