Faculty of Medicine, Damascus University, Damascus, Syria.
Diagnostic Medical Center - Yaman Daaboul Neurophysiology Clinic, Damascus, Syria.
Brain Behav. 2022 Feb;12(2):e2493. doi: 10.1002/brb3.2493. Epub 2022 Jan 18.
Carpal tunnel syndrome (CTS) is a common entrapment neuropathy of the median nerve at the wrist which causes severe symptoms. However, psychological aspects can affect patients' perception of this pain and can cause similar pain in some instances. This study aims to determine the association between symptoms severity, functional status, and nerve conduction studies (NCS) of adult patients with CTS and their anger, anxiety, and depression status.
This case-control study was conducted in clinics in Damascus, Syria. Controls were frequency matched by gender and age from a general clinic. Interviews based on questionnaires were used that included the Boston Carpal Tunnel Questionnaire (BCTQ-A), Hospital Anxiety and Depression Scale (HADS), Dimensions of Anger Reactions Scale-5 (DAR-5), and NCS.
Overall, 242 patients (121 cases) were included in this study. Cases with CTS had significantly higher anxiety and depression when compared to controls, but not higher anger. Cases with higher anxiety, depression, and anger had significantly more CTS symptoms and less functional status. Anxiety was also higher in cases with normal NCS in the case group. When using regression, anxiety and depression remained significantly associated with having CTS.
Anxiety and depression are more prominent with CTS. Furthermore, having anxiety and depression were associated with more CTS symptoms in the hand. Having anger was also associated with more CTS symptoms among cases. These findings emphasize the importance of psychological aspects when having hand pain or CTS symptoms as these patients might have these symptoms despite having normal NCS.
腕管综合征（CTS）是一种常见的正中神经卡压性周围神经病，会引起严重的症状。然而，心理方面可能会影响患者对这种疼痛的感知，并在某些情况下导致类似的疼痛。本研究旨在确定成人 CTS 患者的症状严重程度、功能状态和神经传导研究（NCS）与他们的愤怒、焦虑和抑郁状态之间的关系。
这是一项在叙利亚大马士革诊所进行的病例对照研究。对照组通过性别和年龄与一般诊所进行频率匹配。使用基于问卷的访谈，包括波士顿腕管问卷（BCTQ-A）、医院焦虑和抑郁量表（HADS）、愤怒反应维度量表-5（DAR-5）和 NCS。
共有 242 名患者（121 例）纳入本研究。与对照组相比，CTS 患者的焦虑和抑郁明显更高，但愤怒没有更高。焦虑、抑郁和愤怒较高的病例，CTS 症状和功能状态较差。在病例组中，NCS 正常的病例焦虑也更高。使用回归时，焦虑和抑郁与 CTS 仍显著相关。
焦虑和抑郁在 CTS 中更为突出。此外，在手部存在焦虑和抑郁与 CTS 症状更多相关。在病例中，愤怒也与更多的 CTS 症状相关。这些发现强调了在手部疼痛或 CTS 症状存在时，心理方面的重要性，因为这些患者尽管 NCS 正常，但可能会出现这些症状。
