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棒球棒状胃管在食道癌根治术中行食管胃端侧吻合降低吻合口漏的风险:一项回顾性倾向评分匹配的 613 例对比研究。

Baseball bat-like gastric tube for end-to-side oesophageal-gastric anastomosis decreased risks of anastomotic leakage after oesophagectomy for oesophageal cancer: A retrospective propensity score matched comparative study with 613 patients.

机构信息

Department of Lung Cancer, West China Hospital, Sichuan University, Chengdu, 610041, PR China West China Hospital of Medicine, Sichuan University, Chengdu, 610041, PR China Department of Endoscopy Center, West China Hospital, Sichuan University, Chengdu, 610041, PR China Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, 610041, PR China.

出版信息

Int J Surg. 2022 Feb;98:106227. doi: 10.1016/j.ijsu.2022.106227. Epub 2022 Jan 15.

Abstract

PURPOSE

To investigate the relationship between baseball bat-like gastric tubes for end-to-side oesophageal-gastric anastomosis and occurrence of anastomotic leakage after oesophagectomy for oesophageal cancer.

METHODS

From July 2019 to June 2021, 613 patients with bat-like or narrow gastric tubes for end-to-side oesophageal-gastric anastomosis in oesophagectomy were retrospectively enrolled, in which 120 patients had narrow gastric tubes and 493 had bat-like gastric tubes. Clinical data including baseline characteristics, in-hospital variables and follow-up outcomes were collected.

RESULTS

Higher occurrence of anastomotic leak was observed in the narrow group in the unmatched cohort (14.2%, 17/120 vs. 7.3%, 36/493; P = 0.016) or the matched cohort after Propensity Score Matching (PSM) analysis (14.2%, 17/120 vs. 7.5%, 27/360, P = 0.028) when compared to the bat-like group; Multivariable analysis for risk factors of postoperative anastomotic leak in the unmatched cohort showed that the use of bat-like gastric tube was an independent protective factor (OR: 0.502, 95% CI: 0.270-0.935, P = 0.030).

CONCLUSIONS

Bat-like gastric tube can be used for end-to-side oesophageal-gastric anastomosis in oesophagectomy. This technique by improving blood supply to the area distal to the anastomosis decreased the incidence of anastomotic leak.

摘要

目的

探讨棒球棒状胃管在食管胃端侧吻合术中与食管癌手术后吻合口漏发生的关系。

方法

回顾性纳入 2019 年 7 月至 2021 年 6 月间采用棒球棒状或窄胃管行食管胃端侧吻合术的 613 例食管癌手术患者,其中 120 例采用窄胃管,493 例采用棒球棒状胃管。收集患者的临床基线资料、术中变量和随访结果。

结果

在未匹配队列中,窄胃管组吻合口漏的发生率高于棒球棒状胃管组(14.2%,17/120 比 7.3%,36/493;P=0.016),在倾向性评分匹配(PSM)分析后两组吻合口漏的发生率仍存在差异(14.2%,17/120 比 7.5%,27/360;P=0.028);多因素分析显示,在未匹配队列中,棒球棒状胃管的使用是术后吻合口漏的独立保护因素(OR:0.502,95%CI:0.270-0.935,P=0.030)。

结论

棒球棒状胃管可用于食管癌手术中的食管胃端侧吻合术,该技术通过改善吻合口远端区域的血供,降低了吻合口漏的发生率。

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