通过 RAFT 聚合合成的双气响应荧光两亲嵌段共聚物。

Dual Gas-responsive Fluorescent Diblock Copolymer Synthesized via RAFT Polymerization.

机构信息

School of Petrochemical Engineering, Liaoning Petrochemical University, Fushun, Liaoning, 113001, China.

School of Materials Science and Engineering, North Minzu University, Yinchuan, Ningxia, 750021, China.

出版信息

J Fluoresc. 2022 Mar;32(2):435-442. doi: 10.1007/s10895-021-02877-z. Epub 2022 Jan 19.

DOI:10.1007/s10895-021-02877-z

PMID:35044575

Abstract

Stimulus-responsive polymers with luminescence properties have a wide range of applications in the fields of controlled drug release, fluorescent probes, and biological stents. In this paper, carbon dioxide (CO)/oxygen (O) dual-responsive fluorescent diblock copolymers were synthesized by the reversible addition-fragmentation chain transfer (RAFT) polymerization method with two fluorescent monomers synthesized as its luminescence source, DEAEMA (CO responsive monomer) and tFMA (O responsive monomer). An experimental study demonstrated that the synthesized stimulus-responsive fluorescent polymer had a high sensitivity to CO; the double-responsive fluorescent diblock copolymer could form and achieve the reversal of polymer micelles in the aqueous solution when it was sequentially subjected to the introduction of CO and O.

摘要

具有发光性质的刺激响应性聚合物在控制药物释放、荧光探针和生物支架等领域有广泛的应用。在本文中，通过可逆加成-断裂链转移（RAFT）聚合方法合成了二氧化碳（CO）/氧气（O）双重响应荧光两嵌段共聚物，以两个荧光单体作为其发光源，DEAEMA（CO 响应单体）和 tFMA（O 响应单体）。实验研究表明，所合成的刺激响应荧光聚合物对 CO 具有高灵敏度；当双重响应荧光两嵌段共聚物依次引入 CO 和 O 时，它可以在水溶液中形成并实现聚合物胶束的反转。