Global Health Research Center, Duke Kunshan University, Kunshan, Jiangsu Province, China.
Baylor College of Medicine, Houston, TX, USA.
J Hum Hypertens. 2023 Jan;37(1):74-79. doi: 10.1038/s41371-022-00656-2. Epub 2022 Jan 19.
Suboptimal medication adherence is a major barrier to hypertension control in Kenya, especially among informal urban settlement areas (sometimes referred to as "slums"). The few studies that have specifically explored medication adherence among this population have received discordant results, implying that additional factors which influence medication adherence merit further investigation. This study explores the relationship between family support and medication adherence among people with hypertension in informal settlements in Nairobi, Kenya. We conducted a quantitative survey followed up by semi-structured qualitative interviews. The sampling frame comprised two health facilities in informal settlement areas of the Korogocho neighborhood and participants were recruited via convenience sampling. We performed multiple logistic regressions for quantitative data and thematic analysis for qualitative data. A total of 93 people participated in the survey (mean age: 57 ± 14.7, 66% female). Most participants reported high family support (82%, n = 76) and suboptimal medication adherence (43% by the Morisky Scale; 76% by the Hill-Bone Scale), with no significant associations between family support and medication adherence. During interviews, many participants reported they lacked health knowledge and education. We suggest that the lack of health knowledge among this population may have contributed to a failure for family support to meaningfully translate into improvements in medication adherence. Our results underscore the need for further research to improve hypertension control among this uniquely disadvantaged population, especially with respect to the possible mediating influence of health education on family support and medication adherence.
在肯尼亚,药物治疗依从性差是高血压控制的主要障碍,尤其是在非正式城市住区(有时被称为“贫民窟”)。少数专门针对该人群药物治疗依从性进行探讨的研究得出了不一致的结果,这意味着影响药物治疗依从性的其他因素值得进一步调查。本研究探讨了内罗毕非正式住区高血压患者家庭支持与药物治疗依从性之间的关系。我们进行了一项定量调查,随后进行了半结构化定性访谈。抽样框架包括 Korogocho 社区非正式住区的两个卫生机构,参与者通过便利抽样招募。我们对定量数据进行了多项逻辑回归分析,对定性数据进行了主题分析。共有 93 人参加了调查(平均年龄:57±14.7,66%为女性)。大多数参与者报告家庭支持度较高(82%,n=76),药物治疗依从性较差(Morisky 量表 43%;Hill-Bone 量表 76%),家庭支持与药物治疗依从性之间无显著关联。在访谈中,许多参与者表示他们缺乏健康知识和教育。我们认为,该人群健康知识的缺乏可能导致家庭支持未能显著转化为药物治疗依从性的改善。我们的研究结果强调需要进一步研究,以改善这一独特弱势群体的高血压控制状况,特别是要关注健康教育对家庭支持和药物治疗依从性的可能中介影响。