Zhao Qian, Sun Xue-Yu, Ma Shu-Qi, Miao Meng-Wei, Li Gai-Ling, Wang Jing-Lu, Guo Rui-Xia, Li Liu-Xia
Department of Gynecology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450000, People's Republic of China.
Int J Gen Med. 2022 Jan 11;15:501-511. doi: 10.2147/IJGM.S340066. eCollection 2022.
This study aims to evaluate the clinical value of laparoscopic temporary internal iliac artery blockage (TIIAB) compared with uterine artery embolization (UAE) in type III cesarean scar pregnancy (CSP).
A total of 76 patients with type III CSP admitted to the Department of Gynecology the First Affiliated Hospital of Zhengzhou University between September 2017 and June 2019 were selected for this retrospective study. Thirty-six of them in the study group received TIIAB, and the rest in control group received UAE. Laparoscopic pregnancy tissue was removed from all patients, and the uterine defects were repaired. The absence of remnants was then confirmed using ultrasonography. Follow-ups were performed in the two groups for six months, and the factors of intraoperative blood loss, operation and menelipsis time, 24-h human chorionic gonadotropin decline rate, postoperative complications, hospitalization days, hospitalization costs, peri-operative hormone levels, and ovarian function indicators were compared between the two groups and within each group.
There were statistically significant differences in the hospitalization cost, menelipsis time, and postoperative complication incidence between the two groups (p < 0.05). There were statistically significant differences between ovarian function at one month and three months after surgery (p < 0.05) as well as among the follicle-stimulating hormone, luteinizing hormone, and estradiol levels at one, three, and six months after surgery in the control group (p < 0.05).
Compared with uterine artery embolization, laparoscopic TIIAB has the advantages of a low hospitalization cost, lower postoperative complication rate, and shorter menelipsis time. Moreover, it avoids ovarian function damage. It is a safe method worthy of clinical popularization.
本研究旨在评估腹腔镜下暂时性髂内动脉阻断术(TIIAB)与子宫动脉栓塞术(UAE)相比在Ⅲ型剖宫产瘢痕妊娠(CSP)中的临床价值。
选取2017年9月至2019年6月在郑州大学第一附属医院妇科住院的76例Ⅲ型CSP患者进行这项回顾性研究。其中研究组36例接受TIIAB,其余为对照组,接受UAE。所有患者均通过腹腔镜切除妊娠组织,并修复子宫缺损。然后使用超声检查确认无残留物。对两组患者进行为期6个月的随访,比较两组间及每组内术中出血量、手术及闭经时间、术后24小时人绒毛膜促性腺激素下降率、术后并发症、住院天数、住院费用、围手术期激素水平和卵巢功能指标等因素。
两组间住院费用、闭经时间和术后并发症发生率差异有统计学意义(p<0.05)。术后1个月和3个月时卵巢功能差异有统计学意义(p<0.05),对照组术后1个月、3个月和6个月时促卵泡生成素、促黄体生成素和雌二醇水平差异有统计学意义(p<0.05)。
与子宫动脉栓塞术相比,腹腔镜TIIAB具有住院费用低、术后并发症发生率低、闭经时间短等优点。此外,它避免了卵巢功能损害。是一种值得临床推广的安全方法。