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血液透析和肾移植后女性性关系中的性功能:一项横断面研究。

Sexual function in hemodialysis and post-renal transplant women in a relationship: a cross-sectional study.

机构信息

Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, J. Huttlera 4, 31000, Osijek, Croatia.

Clinic for Gynecology and Obstetrics, Osijek University Hospital, J. Huttlera 4, 31000, Osijek, Croatia.

出版信息

Int Urol Nephrol. 2022 Aug;54(8):2037-2046. doi: 10.1007/s11255-021-03095-z. Epub 2022 Jan 21.

Abstract

PURPOSE

Difficulties in sexual functioning are very frequent in patients with chronic kidney disease (CKD). Sexual dysfunction (SD) can significantly diminish the quality of life (QOL) of affected individuals. The aim of this study was to determine the prevalence of SD in female patients undergoing chronic hemodialysis (CHD) and after renal transplantation (RTx) and to compare these groups with each other and with healthy control.

METHODS

The survey was conducted among 123 female participants in a relationship, 28 of them undergoing CHD, 39 after RTx, and 56 healthy women without CKD. For the assessment of the sexual function and comorbidities, the Female Sexual Function Index (FSFI) questionnaire and Ifudu Comorbidity Index were used, respectively.

RESULTS

Median age of all female participants was 60 (50-68). The median age of female CHD patients was 66 (61.3-72.8), RTx patients 56 (48-61), and the control group 59.5 (47.5-67.75). Among all participants, CHD female patients had the lowest scores in all sexual functioning domains. Compared to their age-adjusted control group, CHD patients had lower scores in desire, orgasm, and FSFI full score, whereas RTx patients had lower total FSFI scores and scores in all domains except for desire compared to their controls. Women with lower education, in marriage, and with more comorbidities had lower scores in sexual function domains.

CONCLUSION

Our study shows that SD in female patients undergoing CHD treatment or those after RTx is substantially higher than that in healthy women. We suggest that female patient treated for CKD should have proper care regarding their sexual health, and differences in demographic and medical factors should be taken into consideration during the treatment management.

摘要

目的

慢性肾脏病(CKD)患者的性功能障碍非常常见。性功能障碍(SD)会显著降低受影响个体的生活质量(QOL)。本研究旨在确定接受慢性血液透析(CHD)和肾移植(RTx)的女性患者中 SD 的患病率,并将这些组与彼此和健康对照组进行比较。

方法

该调查在 123 名有伴侣关系的女性参与者中进行,其中 28 名正在接受 CHD 治疗,39 名接受 RTx 治疗,56 名健康女性无 CKD。为了评估性功能和合并症,使用了女性性功能指数(FSFI)问卷和 Ifudu 合并症指数。

结果

所有女性参与者的中位年龄为 60(50-68)岁。女性 CHD 患者的中位年龄为 66(61.3-72.8)岁,RTx 患者为 56(48-61)岁,对照组为 59.5(47.5-67.75)岁。在所有参与者中,CHD 女性患者在所有性功能领域的得分最低。与年龄匹配的对照组相比,CHD 患者的欲望、高潮和 FSFI 总分较低,而 RTx 患者的总 FSFI 评分以及除欲望外的所有领域评分均较低。受教育程度较低、已婚和合并症较多的女性在性功能领域的得分较低。

结论

我们的研究表明,接受 CHD 治疗或接受 RTx 的女性患者的 SD 明显高于健康女性。我们建议,应关注接受 CKD 治疗的女性患者的性健康,在治疗管理中应考虑到人口统计学和医学因素的差异。

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