Génestal M, Caval E, Lareng L, Cathala B
Ann Anesthesiol Fr. 1978;19(10):881-5.
A study of the effects of dopamine, dobutamine and of isoprenaline was carried out in 20 patients with chronic respiratory insufficiency, 16 of whom had pulmonary arterial hypertension (PAP: 22 mmHg). The following findings emerged: --absence of any significant effect of dobutamine on heart rate,--increase in systolic and mean PAP, after infusion of dobutamine,--increase in systolic and mean PAP, after infusion of dopamine,--decrease in BP after administration of infusion of dobutamine,--decrease in pulmonary arterial resistances under the influence of isoprenaline,--decrease in total systemic resistances after the administration of dobutamine,--increase in ventricular, systolic work after the infusion of dopamine.
对20例慢性呼吸功能不全患者进行了多巴胺、多巴酚丁胺和异丙肾上腺素作用的研究,其中16例患有肺动脉高压(肺动脉压:22 mmHg)。出现了以下结果:——多巴酚丁胺对心率无显著影响,——输注多巴酚丁胺后,收缩压和平均肺动脉压升高,——输注多巴胺后,收缩压和平均肺动脉压升高,——输注多巴酚丁胺后血压下降,——在异丙肾上腺素影响下肺动脉阻力降低,——输注多巴酚丁胺后总全身阻力降低,——输注多巴胺后心室收缩作功增加。