促性腺激素释放激素系统的发育。
Development of the gonadotropin-releasing hormone system.
机构信息
CNRS, IFCE, INRAE, Université de Tours, PRC, Nouzilly, France.
Department of Biological Sciences, University at Albany, Albany, NY, USA.
出版信息
J Neuroendocrinol. 2022 May;34(5):e13087. doi: 10.1111/jne.13087. Epub 2022 Jan 23.
Abstract
This review summarizes the current understanding of the development of the neuroendocrine gonadotropin-releasing hormone (GnRH) system, including discussion on open questions regarding (1) transcriptional regulation of the Gnrh1 gene; (2) prenatal development of the GnRH1 system in rodents and humans; and (3) paracrine and synaptic communication during migration of the GnRH cells.
摘要
本综述总结了目前对神经内分泌促性腺激素释放激素 (GnRH) 系统发育的理解，包括讨论关于（1）Gnrh1 基因的转录调控；（2）啮齿动物和人类 GnRH1 系统的产前发育；和（3）GnRH 细胞迁移过程中的旁分泌和突触通讯等方面的未解决问题。
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