Pytrus Tomasz, Akutko Katarzyna, Kofla-Dłubacz Anna, Stawarski Andrzej
2nd Clinical Department of Paediatrics, Gastroenterology and Nutrition, Medical University of Wroclaw, Skłodowskiej-Curie St. 50/52, 50-369 Wroclaw, Poland.
Pediatr Rep. 2022 Jan 4;14(1):13-19. doi: 10.3390/pediatric14010003.
Endoscopic ultrasonography (EUS) is a diagnostic endoscopy of the upper gastrointestinal tract, during which ultrasound of nearby organs is also performed. It is also possible to perform a fine needle aspiration biopsy. Currently, EUS is performed more frequently in adults. Despite some limitations, this diagnostic method is also more and more often performed in pediatric patients. Eosinophilic esophagitis (EoE) is a chronic inflammatory disease of the esophagus, which also occurs in children, and leads to irreversible fibrosis of the esophagus wall, if left untreated. Traditional methods of diagnosing and monitoring EoE treatment have significant limitations, and the use of EUS and total esophageal wall thickness (TWT) assessment may bring measurable benefits. Several studies have shown an increased thickening of TWT in EoE in children compared to pediatric patients with gastroesophageal reflux disease, and a decrease in TWT in adults who responded to EoE treatment. These results suggest that EUS and TWT measurement may become an important test in diagnostics, monitoring the effectiveness of therapy, assessing disease progression, and in individualizing the method and duration of EoE treatment also in children.
内镜超声检查（EUS）是一种上消化道诊断性内镜检查，在此过程中还会对附近器官进行超声检查。也可以进行细针穿刺活检。目前，EUS在成人中应用更为频繁。尽管存在一些局限性，但这种诊断方法在儿科患者中也越来越常用。嗜酸性食管炎（EoE）是一种食管慢性炎症性疾病，也见于儿童，如果不治疗会导致食管壁不可逆纤维化。传统的EoE诊断和监测治疗方法有显著局限性，而使用EUS和评估食管壁总厚度（TWT）可能会带来可衡量的益处。多项研究表明，与患有胃食管反流病的儿科患者相比，儿童EoE患者的TWT增厚，而对EoE治疗有反应的成人TWT降低。这些结果表明，EUS和TWT测量可能成为诊断、监测治疗效果、评估疾病进展以及使儿童EoE治疗方法和疗程个体化的一项重要检查。
