Kumar Santosh, Soni Praveen Kumar, Chandna Abhishek, Parmar Kalpesh, Gupta Pramod K
Department of Urology, PGIMER, Chandigarh, India.
Department of Biostatistics, PGIMER, Chandigarh, India.
Cent European J Urol. 2021;74(4):528-534. doi: 10.5173/ceju.2021.R1.0050. Epub 2021 Sep 18.
Urinary incontinence is a troublesome complication following radical prostatectomy. Various robot-assisted radical prostatectomy (RARP). We describe our technique (Santosh-PGI) of urethral and urinary bladder mucosa coaptation for early continence following RARP.
We performed a prospective comparative study of patients planned for RARP between July 2018 and December 2019 at our centre. A total of 40 patients were enrolled in the study protocol. Following prostatectomy, patients were alternatively assigned into two groups. In one group, urethral and urinary bladder coaptation sutures were placed in a purse string manner using 3-0 Monocryl sutures and none in the another group. All patients underwent standard end to end vesico-urethral anastomosis as described by Van Velthoven. The urinary catheter was removed on day 10 after surgery. All patients were evaluated on day 1, 30 and 90 after catheter removal.
The two groups, each with 20 patients, were comparable in terms of age, clinical staging and D'Amico risk classification. The operative time, blood loss and surgical margin positivity were comparable. Following catheter removal, 75% of patients in Group A (Mucosal coaptation) and 50% in Group B (Standard technique) were continent (p = 0.264). At 30 and 90 days, 90% and 95% in Group A and 60% and 80% in Group B reported continence respectively (p-0.078). Four patients in group B reported bothersome incontinence at 90 days follow-up.
Urethral and urinary bladder mucosal coaptation is a simple innovative technique for early continence following RARP.
尿失禁是根治性前列腺切除术后一个棘手的并发症。各种机器人辅助根治性前列腺切除术(RARP)。我们描述了我们的技术(Santosh-PGI),用于在RARP术后早期实现尿道与膀胱黏膜贴合以促进控尿。
我们对2018年7月至2019年12月在我们中心计划接受RARP的患者进行了一项前瞻性比较研究。共有40名患者纳入研究方案。前列腺切除术后,患者被交替分配到两组。一组使用3-0单股可吸收缝线以荷包缝合的方式放置尿道和膀胱贴合缝线,另一组则不放置。所有患者均按照范·韦尔特霍芬描述的方法进行标准的端端膀胱尿道吻合术。术后第10天拔除导尿管。所有患者在拔除导尿管后的第1天、第30天和第90天进行评估。
两组各有20名患者,在年龄、临床分期和达米科风险分类方面具有可比性。手术时间、失血量和手术切缘阳性情况相当。拔除导尿管后,A组(黏膜贴合组)75% 的患者和B组(标准技术组)50% 的患者实现了控尿(p = 0.264)。在第30天和第90天,A组分别有90% 和95% 的患者报告实现了控尿,B组分别为60% 和80%(p = 0.078)。B组有4名患者在90天随访时报告存在困扰性尿失禁。
尿道与膀胱黏膜贴合是RARP术后早期实现控尿的一种简单创新技术。