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一例活体肾移植受者的新冠病毒病病例报告:一例实现完全康复的具有挑战性的病例

A Case Report of COVID-19 in a Living Kidney Transplant Recipient: A Challenging Case with Complete Rehabilitation.

作者信息

Poor Zamany Nejat Kermaney Mahtab, Hamidi Madani Mohammad, Bonakdar Hashemi Milad, Zadmehr Alireza, Dadpour Mehdi, Roodneshin Fatemeh

机构信息

Department of Anesthesiology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Resident of Urology, Labbafinezhad Hospital, Urology Nephrology Research Center (UNRC), Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Case Rep Urol. 2022 Jan 17;2022:2517674. doi: 10.1155/2022/2517674. eCollection 2022.

Abstract

Adjustment of immunosuppressive and COVID-19 treatment in terms of drug interactions is still challenging. Herein, we report a 45-year-old woman with end-stage renal disease due to autosomal dominant polycystic diseases (ADPKD) with COVID-19 and pulmonary involvement following kidney transplantation. The patient was properly treated by discontinuation of immunosuppressive drugs, bronchoscopy, and high volume of blood transfusions. The fact that we quickly used early intubation and a new treatment regimen that suppressed immune systems may help physicians develop optimal treatment strategies for similar severe cases. However, this treatment method requires more detailed evaluations due to the contradictory results in reviewing other studies.

摘要

在药物相互作用方面调整免疫抑制治疗和新冠病毒疾病治疗仍然具有挑战性。在此,我们报告一名45岁因常染色体显性多囊肾病(ADPKD)导致终末期肾病的女性,在肾移植后感染新冠病毒且肺部受累。通过停用免疫抑制药物、支气管镜检查和大量输血,该患者得到了妥善治疗。我们迅速采用早期插管和抑制免疫系统的新治疗方案这一事实,可能有助于医生为类似的重症病例制定最佳治疗策略。然而,由于回顾其他研究时结果相互矛盾,这种治疗方法需要更详细的评估。

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本文引用的文献

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Novel coronavirus 2019 pneumonia in a kidney transplant recipient.肾移植受者 2019 年新型冠状病毒肺炎。
Am J Transplant. 2020 Sep;20(9):2599-2601. doi: 10.1111/ajt.15999. Epub 2020 Jun 12.
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Covid-19 and Kidney Transplantation.新冠病毒-19与肾移植
N Engl J Med. 2020 Jun 18;382(25):2475-2477. doi: 10.1056/NEJMc2011117. Epub 2020 Apr 24.
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