Rahardja Richard, Morris Arthur J, Hooper Gary J, Grae Nikki, Frampton Christopher M, Young Simon W
Department of Surgery, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.
Health Quality and Safety Commission, Wellington, New Zealand.
J Arthroplasty. 2022 May;37(5):930-935.e1. doi: 10.1016/j.arth.2022.01.046. Epub 2022 Jan 25.
This study aimed to identify the risk factors, in particular the use of surgical helmet systems (SHSs), for prosthetic joint infection (PJI) after total knee arthroplasty (TKA). Data recorded by the New Zealand Surgical Site Infection Improvement Programme (SSIIP) and the New Zealand Joint Registry (NZJR) were combined and analyzed.
Primary TKA procedures performed between July 2013 and June 2018 that were recorded by both the SSIIP and NZJR were analyzed. Two primary outcomes were measured: (1) PJI within 90 days as recorded by the SSIIP and (2) revision TKA for deep infection within 6 months as recorded by the NZJR. Univariate and multivariate analyses were performed to identify risk factors for both outcomes with results considered significant at P < .05.
A total of 19,322 primary TKAs were recorded by both databases in which 97 patients had a PJI within 90 days as recorded by the SSIIP (0.50%), and 90 patients had a revision TKA for deep infection within 6 months (0.47%) as recorded by the NZJR. An SHS was associated with a lower rate of PJI (adjusted odds ratio [OR] = 0.50, P = .008) and revision for deep infection (adjusted OR = 0.55, P = .022) than conventional gowning. Male sex (adjusted OR = 2.6, P < .001) and an American Society of Anesthesiologists score >2 were patient risk factors for infection (OR = 2.63, P < .001 for PJI and OR = 1.75, P = .017 for revision for deep infection).
Using contemporary data from the SSIIP and NZJR, the use of the SHS was associated with a lower rate of PJI after primary TKA than conventional surgical gowning. Male sex and a higher American Society of Anesthesiologists score continue to be risk factors for infection.
本研究旨在确定全膝关节置换术(TKA)后假体关节感染(PJI)的危险因素,特别是手术头盔系统(SHS)的使用情况。将新西兰手术部位感染改善计划(SSIIP)和新西兰关节登记处(NZJR)记录的数据进行合并和分析。
对2013年7月至2018年6月期间由SSIIP和NZJR记录的初次TKA手术进行分析。测量了两个主要结局:(1)SSIIP记录的90天内的PJI;(2)NZJR记录的6个月内因深部感染进行的TKA翻修术。进行单因素和多因素分析以确定这两个结局的危险因素,结果在P <.05时被认为具有统计学意义。
两个数据库共记录了19322例初次TKA手术,其中SSIIP记录有97例患者在90天内发生PJI(0.50%),NZJR记录有90例患者在6个月内因深部感染进行了TKA翻修术(0.47%)。与传统手术衣相比,SHS与较低的PJI发生率(调整后的优势比[OR]=0.50,P=.008)和深部感染翻修率(调整后的OR=0.55,P=.022)相关。男性(调整后的OR=2.6,P<.001)和美国麻醉医师协会评分>2是感染的患者危险因素(PJI的OR=2.63,P<.001;深部感染翻修术的OR=1.75,P=.017)。
使用来自SSIIP和NZJR的当代数据,与传统手术衣相比,SHS的使用与初次TKA后较低的PJI发生率相关。男性和较高的美国麻醉医师协会评分仍然是感染的危险因素。