Department of Digestive Surgery, University Hospital of Caen, Caen cedex, France; UFR de Médecine, Caen, France.
Department of Digestive Surgery, University Hospital of Caen, Caen cedex, France; UFR de Médecine, Caen, France; UMR INSERM 1086 "Cancers et preventions," Centre François Baclesse, Caen, France.
Surg Obes Relat Dis. 2022 Apr;18(4):520-529. doi: 10.1016/j.soard.2021.12.011. Epub 2021 Dec 28.
Patients over 60 years old undergoing bariatric surgery is still increasing.
First, to assess the impact of age (>60 years) on the 90-day morbidity and mortality of both laparoscopic Roux-en-Y gastric bypass (LRYGB) and sleeve gastrectomy (LSG), and second, to determine the effectiveness of surgical weight loss and resolution of obesity-related comorbidities for patients 60 years of age and older over a 2-year period.
Bicentric study from University Hospital of Caen and Memorial Hospital of Saint Lô, France.
This is a retrospective review of a prospectively maintained database of patients with morbid obesity undergoing laparoscopic bariatric surgery from October 2005 to April 2019. Patients 60 years of age and older were defined as cases (elderly group [EG], n = 137), and patients younger than 60 years of age were defined as controls (young group [YG], n = 1544). The primary endpoint of the study was the prevalence of severe postoperative complications within 90 days of surgery determined by a propensity-score-matching (PSM) analysis.
The PSM population included 133 patients in the EG who were matched 1:2 with 266 patients in the YG. There was no mortality in either group. Although not significant (with an absolute difference of 4.5% between the EG and the YG), the odds of severe postoperative complications were 2.5 times higher in the EG than in the YG (7.5% versus 3.0%, P = .053). At 90 days postoperatively, the prevalences of overall morbidity (31.6% versus 22.9%, P = .044), leakage (5.3% versus 1.1%, P = .026), and reoperation (5.3% versus 1.1%, P = .026) were significantly higher in the EG than in the YG.
This propensity-matched study suggests that laparoscopic bariatric surgery is probably an effective treatment in obese elderly patients (EPs) in terms of weight loss and resolution of comorbidities. However, the EP should be warned of the increased risk of severe postoperative complications within 90 days, including leakage and reoperation rates, especially after RYGB.
接受减重手术的 60 岁以上患者仍在增加。
首先,评估年龄(>60 岁)对腹腔镜 Roux-en-Y 胃旁路术(LRYGB)和袖状胃切除术(LSG)术后 90 天发病率和死亡率的影响;其次,确定对于 60 岁及以上患者,在 2 年期间手术减肥和解决肥胖相关合并症的效果。
法国卡昂大学医院和圣洛纪念医院的双中心研究。
这是一项回顾性研究,对 2005 年 10 月至 2019 年 4 月期间接受腹腔镜减重手术的病态肥胖患者的前瞻性数据库进行了回顾。年龄 60 岁及以上的患者被定义为病例(老年组[EG],n=137),年龄小于 60 岁的患者被定义为对照组(年轻组[YG],n=1544)。研究的主要终点是通过倾向评分匹配(PSM)分析确定术后 90 天内严重术后并发症的发生率。
PSM 人群中包括 133 例 EG 患者,与 YG 中的 266 例患者匹配 1:2。两组均无死亡病例。虽然无统计学意义(EG 和 YG 之间绝对差异为 4.5%),但 EG 发生严重术后并发症的几率是 YG 的 2.5 倍(7.5%比 3.0%,P=0.053)。术后 90 天,EG 的总体发病率(31.6%比 22.9%,P=0.044)、漏液(5.3%比 1.1%,P=0.026)和再次手术(5.3%比 1.1%,P=0.026)的发生率明显高于 YG。
这项倾向评分匹配研究表明,腹腔镜减重手术可能是肥胖老年患者(EPs)治疗肥胖和解决合并症的有效方法。然而,应警告 EP 在术后 90 天内发生严重术后并发症的风险增加,包括漏液和再次手术的发生率,尤其是在 RYGB 后。