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黎巴嫩减重手术实践中腹腔镜Roux-en-Y胃旁路术与袖状胃切除术的疗效比较。

Comparison of Outcomes Between Laparoscopic Roux-en-Y Gastric Bypass and Sleeve Gastrectomy in a Lebanese Bariatric Surgical Practice.

作者信息

Dakour Aridi Hanaa, Khazen Georges, Safadi Bassem Y

机构信息

Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon.

Computer Science and Mathematics Department, Lebanese American University, Byblos, Lebanon.

出版信息

Obes Surg. 2018 Feb;28(2):396-404. doi: 10.1007/s11695-017-2849-5.

Abstract

PURPOSE

Long-term studies on the outcomes of bariatric surgery are still limited in the Middle East. The aim of this study is to compare the outcomes of laparoscopic Roux-en-Y gastric bypass (LRYGB) and sleeve gastrectomy (LSG) up to 5 years of follow-up.

MATERIALS AND METHODS

A retrospective analysis of patients who underwent LRYGB and LSG was performed. The primary outcome was weight loss. Postoperative complications, operative time, and hospital length of stay were secondary outcomes.

RESULTS

Four hundred patients underwent primary LSG and 175 patients underwent LRYGB between 2008 and 2013. Follow-up rates at 5 years were around 60%. Percent total weight loss was similar after 3, 4, and 5 years in both groups, averaging around 28%. Mean percentage of excess weight loss (%EWL) at 5 years was 72.0 ± 31.0% in the LSG group vs. 63.0 ± 21.0% in the LRYGB group (p = 0.03). Patients undergoing LRYGB had a significantly longer operative time as well as a longer hospital stay. No significant difference was found in the rates of short- and long-term complications between the two groups. However, patients undergoing LRYGB were more likely to develop small intestinal obstruction and iron-deficiency anemia.

CONCLUSIONS

Both LSG and LRYGB result in satisfactory weight loss within 5 years. Patients' comorbidities and potential risks must be included in the choice of the appropriate bariatric procedure. LSG appears to give durable weight loss with less risk of major long-term complications.

摘要

目的

中东地区关于减肥手术长期疗效的研究仍然有限。本研究的目的是比较腹腔镜Roux-en-Y胃旁路术(LRYGB)和袖状胃切除术(LSG)长达5年的随访结果。

材料与方法

对接受LRYGB和LSG的患者进行回顾性分析。主要结局指标是体重减轻。术后并发症、手术时间和住院时间是次要结局指标。

结果

2008年至2013年间,400例患者接受了初次LSG,175例患者接受了LRYGB。5年的随访率约为60%。两组在3年、4年和5年后的总体重减轻百分比相似,平均约为28%。LSG组5年时的平均超重减轻百分比(%EWL)为72.0±31.0%,而LRYGB组为63.0±21.0%(p = 0.03)。接受LRYGB的患者手术时间明显更长,住院时间也更长。两组在短期和长期并发症发生率方面未发现显著差异。然而,接受LRYGB的患者更有可能发生小肠梗阻和缺铁性贫血。

结论

LSG和LRYGB在5年内均能带来令人满意的体重减轻。在选择合适的减肥手术时,必须考虑患者的合并症和潜在风险。LSG似乎能带来持久的体重减轻,且发生重大长期并发症的风险较低。

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