Ranjbar Fahimeh, Catja Warmelink Comma Comma J, Mousavi Robab, Gharacheh Maryam
Nursing Care Research Center, Iran University of Medical Sciences, Tehran, Iran.
Department of Midwifery Science, Amsterdam Public Health Research Institute, VU University Medical Center, Amsterdam, the Netherlands.
Int J Reprod Biomed. 2022 Jan 12;19(12):1075-1084. doi: 10.18502/ijrm.v19i12.10058. eCollection 2021 Dec.
Pregnancy through assisted reproductive technology (ART) is a stressful experience that may affect prenatal attachment. However, maternal-fetal attachment (MFA) and anxiety in pregnancy after ART are understudied in Iran.
To compare changes in MFA and pregnancy-related anxiety (PRA) in the first and third trimester of pregnancy in women who conceived through ART compared to those who conceived naturally.
This longitudinal study was conducted in 2019 with 187 pregnant women (ART conception = 43, natural conception = 144). Participants were recruited using the consecutive sampling method from a prenatal clinic in Tehran. The Cranley MFA Scale and the Van Den Bergh PRA Questionnaire were used to collect the data.
The MFA score in the 12 wk of gestation was lower in the women who conceived with ART compared to in the women who conceived naturally, but there was no statistically significant difference between the groups in wk 36. MFA in both groups was significantly higher at gestational wk 36 than wk 12 (p 0.001). The increase in MFA score was significantly higher in the women who conceived with ART than in those who conceived naturally (p 0.001). The anxiety score declined in the two groups and no statistically significant difference was observed in the changes of anxiety scores between the two groups (p = 0.84).
Pregnant women who conceived through ART were as attached to their fetus in the third trimester of pregnancy as other women and did not experience more PRA.
通过辅助生殖技术（ART）怀孕是一段压力较大的经历，可能会影响产前依恋。然而，在伊朗，ART 后孕期的母婴依恋（MFA）和焦虑情况尚未得到充分研究。
比较通过 ART 受孕的女性与自然受孕的女性在妊娠早期和晚期 MFA 和妊娠相关焦虑（PRA）的变化。
这项纵向研究于 2019 年对 187 名孕妇进行（ART 受孕 = 43 例，自然受孕 = 144 例）。采用连续抽样法从德黑兰一家产前诊所招募参与者。使用克兰利 MFA 量表和范登伯格 PRA 问卷收集数据。
与自然受孕的女性相比，通过 ART 受孕的女性在妊娠 12 周时的 MFA 得分较低，但在 36 周时两组之间无统计学显著差异。两组在妊娠 36 周时的 MFA 均显著高于 12 周时（p < 0.001）。通过 ART 受孕的女性 MFA 得分的增加显著高于自然受孕的女性（p < 0.001）。两组的焦虑得分均下降，两组焦虑得分的变化无统计学显著差异（p = 0.84）。
通过 ART 受孕的孕妇在妊娠晚期与其他女性一样依恋胎儿，且未经历更多的 PRA。
