Universidad UTE, Centro Asociado Cochrane de Ecuador, Centro de Investigación de Salud Pública y Epidemiología Clínica (CISPEC), Quito, Ecuador; Proyecto Epistemonikos, Santiago, Chile.
Proyecto Epistemonikos, Santiago, Chile; Centro Evidencia UC, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Medwave. 2022 Jan 28;22(1):e8320. doi: 10.5867/medwave.2022.01.8320.
Dental caries have been traditionally managed with the non-selective removal of carious tissue (total removal). However, the adverse effects and fear that this technique produces in patients has promoted the use of more conservative caries removal techniques such as chemo-mechanical removal, but there is still controversy regarding its effectiveness and safety.
We searched in Epistemonikos, the largest database of systematic reviews in health, which is maintained by screening multiple information sources, including MEDLINE, EMBASE, Cochrane, among others. We extracted data from the systematic reviews, reanalyzed data of primary studies, conducted a meta-analysis and generated a summary of findings tables using the GRADE approach.
We identified seven systematic reviews including 34 studies overall, of which 30 correspond to randomized trials. We concluded that chemo-mechanical caries removal probably reduces the need for anesthesia. Additionally, chemo-mechanical caries removal may decrease the pain experienced by the patient, decrease the risk of restoration failure and increase the time of the procedure for the removal of deep caries, but the certainty of the evidence is low. We are uncertain whether chemo-mechanical caries removal reduces the risk of pulp exposure as the certainty of the evidence has been assessed as very low.
龋齿的传统治疗方法是采用非选择性的去除龋坏组织(全部去除)。然而,这种技术会给患者带来不良影响和恐惧,因此促进了更保守的去龋技术的应用,如化学机械去龋,但关于其有效性和安全性仍存在争议。
我们在 Epistemonikos 中进行了搜索,这是一个最大的健康系统评价数据库,通过筛选多个信息来源(包括 MEDLINE、EMBASE、Cochrane 等)来维护该数据库。我们从系统评价中提取数据,重新分析原始研究的数据,进行荟萃分析,并使用 GRADE 方法生成结果总结表。
我们共纳入了 7 篇系统评价,共包含 34 项研究,其中 30 项为随机试验。我们的结论是,化学机械去龋可能会减少对麻醉的需求。此外,化学机械去龋可能会减轻患者的疼痛,降低修复失败的风险,并增加深龋去除过程的时间,但证据的确定性较低。我们不确定化学机械去龋是否会降低牙髓暴露的风险,因为证据的确定性被评估为非常低。