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肝移植中的血管造影及介入放射学考量

Angiographic and interventional radiologic considerations in liver transplantation.

作者信息

Cardella J F, Castaneda-Zuniga W R, Hunter D, Young A, Amplatz K

出版信息

AJR Am J Roentgenol. 1986 Jan;146(1):143-53. doi: 10.2214/ajr.146.1.143.

Abstract

Of 46 liver transplantations performed, 15 patients are alive at follow-up intervals from 2 to 50 months. The most common indications for liver transplantation were biliary atresia, cirrhosis, and neoplasia. About 50% of the patients had pre- and/or postoperative angiograms. Additional material was available from pretransplant workups in patients subsequently shown to be unsuitable for transplantation. Of 13 preoperative angiographic studies, portal vein patency was confirmed in two, inferior vena caval (IVC) patency was confirmed in two, and diffuse neoplasm was identified in three. These patients subsequently had transplants. Conditions precluding liver transplantation in six patients were inadequate portal vein size (less than 5 mm) in two, occluded IVC or portal vein in one each, nonvisualized portal vein in one, and neoplasm localized to one lobe in one. Postoperatively 18 vascular studies identified hepatic arterial compromise in nine, postbiopsy arteriovenous fistula in two, and bleeding from a right adrenal artery in one. Postoperative venography showed thrombosis or occlusion of the IVC in five, portal vein thrombosis in one, and splenic vein thrombosis in one. Of the 18 postoperative angiograms, 12 demonstrated findings considered threatening to the transplants' survival. Six of 18 studies demonstrated findings considered compromising to the transplant. Of the nine postoperative cholangiographic studies, six diagnoses were considered threatening to transplant survival: obstruction of the biliary-enteric anastomosis in four, leakage from the biliary-enteric anastomosis in one, and an abscess from biliary leakage in one.

摘要

在进行的46例肝移植手术中,15例患者在2至50个月的随访期内存活。肝移植最常见的适应证是胆道闭锁、肝硬化和肿瘤。约50%的患者术前行了血管造影,术后也进行了血管造影。另外,从随后被证明不适合移植的患者的移植前检查中也获得了相关资料。在13例术前血管造影研究中,2例证实门静脉通畅,2例证实下腔静脉通畅,3例发现弥漫性肿瘤。这些患者随后接受了移植手术。6例患者因以下情况而无法进行肝移植:2例门静脉直径过小(小于5毫米),1例下腔静脉或门静脉闭塞,1例门静脉不显影,1例肿瘤局限于一个肝叶。术后18例血管造影检查发现9例肝动脉受损,2例活检后出现动静脉瘘,1例右肾上腺动脉出血。术后静脉造影显示5例下腔静脉血栓形成或闭塞,1例门静脉血栓形成,1例脾静脉血栓形成。在18例术后血管造影中,12例显示的结果被认为对移植肝的存活构成威胁。18例研究中有6例显示的结果被认为对移植有不利影响。在9例术后胆管造影研究中,6例诊断结果被认为对移植存活构成威胁:4例胆肠吻合口梗阻,1例胆肠吻合口漏,1例胆漏形成脓肿。

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