University of California, Los Angeles, David Geffen School of Medicine.
Cutis. 2021 Nov;108(5):289-291. doi: 10.12788/cutis.0387.
Annular erythemas of infancy (AEIs) are rare benign skin eruptions characterized by persistent, annular, urticarial, nonpruritic patches and plaques that develop in patients younger than 1 year. Histologically, a skin biopsy typically demonstrates a perivascular infiltrate in the dermis composed of small lymphocytes, neutrophils, and increased scattered eosinophils. We report a case of an AEI in an 11-month-old girl with uncommon histologic features. Recognition of these benign cells is important to avoid misdiagnosing them as atypical or neoplastic. We also provide a review of the differential diagnosis for AEIs.
婴儿环状红斑(AEI)是一种罕见的良性皮肤疹,其特征为持续存在的环状、荨麻疹样、非瘙痒性斑块和斑片,发生于 1 岁以下的患者。组织学上,皮肤活检通常显示真皮中的小淋巴细胞、中性粒细胞和增多的散在嗜酸性粒细胞的血管周围浸润。我们报告了一例 11 个月大女孩的 AEI,其具有罕见的组织学特征。认识到这些良性细胞很重要,以避免将其误诊为非典型或肿瘤性。我们还提供了 AEI 的鉴别诊断综述。