Robinson G E, Stewart D E
CMAJ. 1986 Jan 1;134(1):31-7.
Postpartum blues, postpartum neurotic depression and puerperal psychoses have distinct clinical features; they affect women in all social classes and in all cultures, and despite numerous studies they have not been linked definitively with any biologic or psychosocial variables. The only possible exception is puerperal psychosis, which emerges much more often in women with a personal or family history of a bipolar affective disorder than in women without, a finding that probably explains the reluctance of some researchers to recognize puerperal psychotic episodes as distinct from psychotic episodes at other times. If postpartum blues last longer than 2 weeks and are disabling they are classified as neurotic depression and warrant treatment, often requiring both psychosocial approaches and psychotropic drug therapy. Antidepressants, major tranquillizers, electroconvulsive therapy and lithium have proved effective in the treatment of postpartum psychoses, depending on the symptoms. Both lithium and diazepam have been reported to cause deleterious side effects on breast-fed infants, and as the side effects of other psychotropic drugs given to a nursing mother are imperfectly understood, bottle feeding seems prudent.
产后情绪低落、产后神经性抑郁和产褥期精神病有明显的临床特征;它们影响着所有社会阶层和所有文化背景的女性,尽管有大量研究,但它们尚未与任何生物学或社会心理变量明确关联。唯一可能的例外是产褥期精神病,有双相情感障碍个人或家族病史的女性比没有此类病史的女性更易出现产褥期精神病,这一发现或许解释了一些研究人员不愿将产褥期精神病发作与其他时期的精神病发作区分开来的原因。如果产后情绪低落持续超过两周且导致功能障碍,就会被归类为神经性抑郁并需要治疗,通常需要社会心理方法和精神药物治疗相结合。根据症状不同,抗抑郁药、大剂量镇静剂、电休克疗法和锂盐已被证明对治疗产褥期精神病有效。据报道,锂盐和地西泮都会对母乳喂养的婴儿产生有害副作用,而且由于对给哺乳期母亲使用的其他精神药物的副作用了解不全面,采用人工喂养似乎更为谨慎。