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穴位自血疗法成功治疗顽固性特应性皮炎:一例报告及该疗法的机制假说

Successfully treated recalcitrant atopic eczema with acupoint autohemotherapy: A case report and hypothesized mechanism of the therapy.

作者信息

Zhao Bin, Chen Yong, Liao Shi-Min, Zheng Jian-Ying, Yan Shi-Hua, Zhang Dong-Shu

机构信息

Department of Acupuncture, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong Province, China; Department of Acupuncture, College of Traditional Chinese Medicine, Southern Medical University, Guangzhou 510515, Guangdong Province, China.

Department of Rheumatology and Immunology, Shenzhen People's Hospital, the Second Clinical Medical College of Jinan University, Shenzhen 518020, Guangdong Province, China.

出版信息

J Integr Med. 2022 Mar;20(2):182-186. doi: 10.1016/j.joim.2022.01.003. Epub 2022 Jan 13.

Abstract

Acupoint autohemotherapy at bilateral Zusanli (ST36) and Xuehai (SP10) was used to treat a 26-year-old female patient who had suffered from recalcitrant atopic eczema (AE) for five years. The treatment was applied at a frequency of once per week for the first month, followed by a three-month period of once every other week. At the end of treatment, the patient's AE symptoms were entirely resolved, and by the end of a six-month follow-up her immunoglobulin E level had returned to the normal range. Further, there was no relapse of AE symptoms during the six-month follow-up. Therefore, we hypothesized that after the repeated treatments the local inflammatory reaction induced by autologous blood injection triggered a local immune response, followed by a systemic immune response after the repeated treatment, finally leading to the anti-inflammation and immunomodulation effects. This case suggests that acupoint autohemotherapy could be used as an effective complementary treatment for recalcitrant AE, especially in cases where other treatments have failed. Further comparative studies are needed to corroborate the value and mechanisms of this therapy.

摘要

采用双侧足三里(ST36)和血海(SP10)穴位自血疗法治疗一名患有顽固性特应性皮炎(AE)五年的26岁女性患者。治疗频率为第一个月每周一次,随后三个月每两周一次。治疗结束时,患者的AE症状完全缓解,在六个月随访结束时,其免疫球蛋白E水平恢复到正常范围。此外,在六个月随访期间AE症状未复发。因此,我们推测,重复治疗后自体血注射诱导的局部炎症反应引发局部免疫反应,重复治疗后继而引发全身免疫反应,最终导致抗炎和免疫调节作用。该病例表明,穴位自血疗法可作为顽固性AE的有效辅助治疗方法,尤其是在其他治疗方法无效的情况下。需要进一步的对照研究来证实该疗法的价值和机制。

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