Zeng Zhiwen, Li Man, Zeng Yunjie, Zhang Jialing, Zhao Yingjie, Lin Yuanxun, Qiu Ruijin, Zhang Dong-Shu, Shang Hong-Cai
Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong, China.
Evid Based Complement Alternat Med. 2021 Jun 26;2021:9994824. doi: 10.1155/2021/9994824. eCollection 2021.
Acupuncture is considered a complementary therapy for atopic eczema. The aim of this scoping review is to identify, examine, and summarize the potential acupoint prescriptions and outcome reporting regarding the clinical trials of acupuncture for eczema.
We searched different databases from inception to September 30, 2020. The data were screened and extracted to identify the potential acupuncture prescription and examine the variation in outcome reporting, outcome measurement instruments (OMIs), and measurement time points in clinical trials of acupuncture.
A total of 116 clinical studies were included. The acupoint combination of LI11 and SP10 was used frequently. The core acupoint association networks were acupoints LI11, SP10, ST36, SP6, and LI4. For clinical trials of acupuncture, a total of 6 outcome distinct domains were identified in the 32 outcome measurements. The most frequently reported outcome was the eczema area, which was reported 97 times (83.6%, 97/116). Immune system outcomes were assessed in 15 outcome measurements, which totally reported 37 times. Adverse events were reported 51 times. TCM syndrome, which could reflect the characteristics of TCM, was reported 4 times. 29 outcomes (90.6%, 29/32) were provided definitions or OMIs. Among these outcomes, the outcome measurement times ranged from 0 to 34.
This scoping review provides potential knowledge that should be considered as priority in future research of acupuncture for eczema.
针灸被认为是特应性皮炎的一种补充疗法。本综述的目的是识别、审查和总结有关针灸治疗湿疹临床试验的潜在穴位处方和结果报告。
我们检索了从数据库建立到2020年9月30日的不同数据库。对数据进行筛选和提取,以识别潜在的针灸处方,并审查针灸临床试验中结果报告、结果测量工具(OMIs)和测量时间点的差异。
共纳入116项临床研究。合谷(LI11)和血海(SP10)的穴位组合使用频繁。核心穴位关联网络为合谷(LI11)、血海(SP10)、足三里(ST36)、三阴交(SP6)和手三里(LI4)。在针灸临床试验中,在32项结果测量中总共确定了6个不同的结果领域。最常报告的结果是湿疹面积,报告了97次(83.6%,97/116)。在15项结果测量中评估了免疫系统结果,总共报告了37次。报告了51次不良事件。反映中医特点的中医证候报告了4次。29项结果(90.6%,29/32)提供了定义或OMIs。在这些结果中,结果测量时间范围为0至34。
本综述提供了潜在的知识,应在未来针灸治疗湿疹的研究中作为优先考虑。