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稳定期慢性淋巴细胞白血病中的非典型脓肿分枝杆菌感染:一例报告及文献复习

Atypical Mycobacterium Abscessus Infection in Stable Chronic Lymphocytic Leukemia: A Case Report and Review of the Literature.

作者信息

Rodriguez Robin R, Alhamad Khaled, Ghosh Sohini, Bihler Eric, Raj Moses S

机构信息

Medical Oncology, Allegheny Health Network, Pittsburgh, USA.

Internal Medicine, Allegheny Health Network, Pittsburgh, USA.

出版信息

Cureus. 2021 Dec 21;13(12):e20574. doi: 10.7759/cureus.20574. eCollection 2021 Dec.

DOI:10.7759/cureus.20574
PMID:35103153
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8776059/
Abstract

Chronic lymphocytic leukemia is the most common blood cancer in adults. A major cause of morbidity and mortality associated with this cancer stems from opportunistic infections. Similar to many cancers, the inherent effects of battling a raging disease along with the many treatment options causing immunosuppression to lend to the likelihood of obtaining secondary infections. As it is important for physicians to note the ever-increasing secondary complications, which can manifest in the long-term management of immunosuppressed patients, we present a case of an 86-year-old Caucasian female with stable chronic lymphocytic leukemia who developed intermittent presentation of lung abscesses due to growth of atypical species. With the advent of new treatment options, there has been an increased rate of drug-resistant organisms, lending for the need for more awareness to the severity of these secondary complications and for better options in preventing their occurrence.

摘要

慢性淋巴细胞白血病是成人中最常见的血液癌症。与这种癌症相关的发病和死亡的主要原因源于机会性感染。与许多癌症一样,对抗这种肆虐疾病的内在影响以及许多导致免疫抑制的治疗选择增加了获得继发性感染的可能性。由于医生注意到不断增加的继发性并发症很重要,这些并发症可能在免疫抑制患者的长期管理中出现,我们报告一例86岁白种女性病例,她患有稳定的慢性淋巴细胞白血病,因非典型菌种生长而出现间歇性肺脓肿。随着新治疗选择的出现,耐药菌的发生率有所增加,这就需要更多地认识到这些继发性并发症的严重性,并需要更好的预防其发生的选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98c2/8776059/9b4e066a62a4/cureus-0013-00000020574-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98c2/8776059/9b4e066a62a4/cureus-0013-00000020574-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98c2/8776059/9b4e066a62a4/cureus-0013-00000020574-i01.jpg

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