多发性骨髓瘤中急性脑病的罕见病因

An Uncommon Cause of Acute Encephalopathy in Multiple Myeloma.

作者信息

Al Zeyoudi Jawaher, Al Naqbi Aisha, Kashiwagi Deanne, Siddiqui Mustaqeem

机构信息

Internal Medicine, Sheikh Khalifa Medical City, Abu Dhabi, ARE.

Internal Medicine, Sheikh Shakbout Medical City, Abu Dhabi, ARE.

出版信息

Cureus. 2021 Dec 22;13(12):e20605. doi: 10.7759/cureus.20605. eCollection 2021 Dec.

DOI:10.7759/cureus.20605

PMID:35103181

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8781650/

Abstract

Multiple myeloma commonly presents with bone pain, pathological fractures, hypercalcemia, anemia, and acute kidney injury. Altered mental status due to multiple myeloma is generally attributed to uremia, hypercalcemia, and hyperviscosity. In this report, we present a rare case of altered mental status due to high serum ammonia levels in a patient with advanced multiple myeloma and with no liver dysfunction.

摘要

多发性骨髓瘤通常表现为骨痛、病理性骨折、高钙血症、贫血和急性肾损伤。多发性骨髓瘤所致的精神状态改变一般归因于尿毒症、高钙血症和血液黏稠度增加。在本报告中，我们呈现了1例晚期多发性骨髓瘤患者因血清氨水平升高导致精神状态改变的罕见病例，该患者并无肝功能障碍。