Dryden Stephen C, Gabbard Ryan D, Meador Andrew G, Stoner Alison E, Klippenstein Kimberly A, Wesley Ralph E
Ophthalmology, Tennessee Oculoplastics, Nashville, USA.
Ophthalmology, Prisma Health/University of South Carolina, Columbia, USA.
Cureus. 2021 Dec 22;13(12):e20606. doi: 10.7759/cureus.20606. eCollection 2021 Dec.
A foreign body granulomatous reaction is a rare complication of the subcutaneous injection of fillers. We describe a 57-year-old female that presented with a six-month history of a non-painful, right lower eyelid mass. She had a dermal filler in the zygomatic region several months before the onset of her symptoms. Anterior orbitotomy and pathology revealed multinuclear giant cells consistent with a hyaluronic acid-based filler. This case describes the clinical presentation, histopathologic features, and treatment of an orbital granuloma secondary to dermal filler injection. Our case was uncommon because the zygomatic filler migrated across the orbital septum. Additionally, transconjunctival orbitotomy was used instead of a hyaluronidase injection due to the inferior location of the granuloma.
异物性肉芽肿反应是皮下注射填充剂的一种罕见并发症。我们描述了一名57岁女性，她有一个无痛性右下眼睑肿物，病史长达6个月。在症状出现前几个月，她在颧部注射了真皮填充剂。前路眶切开术及病理检查发现多核巨细胞，与基于透明质酸的填充剂相符。本病例描述了真皮填充剂注射继发眼眶肉芽肿的临床表现、组织病理学特征及治疗方法。我们的病例不常见，因为颧部填充剂穿过了眶隔。此外，由于肉芽肿位置较低，采用了经结膜眶切开术而非注射透明质酸酶。
