Boumrah Yacine, Kermouche Wissam, Zarita Bouzid, Drardja El Djemai, Bouanani Sabrina
Toxicology Department, National Institute of Criminalistics and Criminology (INCC-GN), Algiers, Algeria.
J Forensic Sci. 2022 May;67(3):889-898. doi: 10.1111/1556-4029.15001. Epub 2022 Feb 1.
In Algeria, hashish is by far the most common illicit drug. This study explores Algerian hashish over a two-year period (2019-2020). A total of 2583 hashish samples from 1707 seizures for a total quantity of 108 tons were analyzed using a validated high-performance liquid chromatography-diode array detection method (HPLC-DAD). The yearly arithmetic mean tetrahydrocannabinol (THC) concentration shows relative stability-18.67% in 2019 and 19.03% in 2020 with an overall mean THC content of 18.87% and standard deviation of 10.99%. High-potency hashish (THC content > 20%) is by far the most predominant type, representing almost 50% of the total Algerian hashish seizures (mean and median around 29%). The overall mean of cannabidiol (CBD) was 2.45%, and 12% of the total studied seizures were of very low CBD concentration (CBD content<1%). Three distinct hashish chemotypes were identified: Chemotype I described the traditional Moroccan hashish with THC content ranging from 0% to 16%, Chemotype II hashish included most of the seizures and characterized by THC content ranging from 16% to 30%, and Chemotype III was characterized by hashish potency higher than 30% and very low CBD content. The identified chemotypes I, II, and III were characterized in a ternary plot, and the relative contents (THC:CBD:CBN) were about 67%:29%:4%, 88%:9%:3%, and 96%:2%:2%, respectively.
在阿尔及利亚,大麻是目前最常见的非法药物。本研究对2019年至2020年这两年间的阿尔及利亚大麻进行了探索。使用经过验证的高效液相色谱 - 二极管阵列检测方法(HPLC - DAD)对来自1707次缉获行动的总共2583个大麻样本进行了分析,这些样本的总量为108吨。年度算术平均四氢大麻酚(THC)浓度显示出相对稳定性——2019年为18.67%,2020年为19.03%,总体平均THC含量为18.87%,标准差为10.99%。高浓度大麻(THC含量>20%)是迄今为止最主要的类型,占阿尔及利亚大麻缉获总量的近50%(均值和中位数约为29%)。大麻二酚(CBD)的总体平均值为2.45%,在所研究的缉获总量中,12%的样本CBD浓度非常低(CBD含量<1%)。确定了三种不同的大麻化学类型:化学类型I描述的是传统摩洛哥大麻,THC含量范围为0%至16%;化学类型II大麻包括了大部分缉获样本,其特征是THC含量范围为16%至30%;化学类型III的特征是大麻效力高于30%且CBD含量非常低。在三元图中对所确定的化学类型I、II和III进行了表征,其相对含量(THC:CBD:CBN)分别约为67%:29%:4%、88%:9%:3%和96%:2%:2%。