Rigsby C M, Taylor K J, Weltin G, Burns P N, Bia M, Princenthal R A, Kashgarian M, Flye M W
Radiology. 1986 Feb;158(2):375-8. doi: 10.1148/radiology.158.2.3510443.
Sixty-nine duplex sonographic studies were performed in 24 patients who had received renal allografts. After a prospective qualitative analysis of the Doppler waveforms, results were correlated with biopsy material and each patient's clinical course. Increased pulsatility of the Doppler waveform of intrarenal arterial flow constituted an abnormal study, indicating acute rejection. Overall sensitivity varied with the histologic form of rejection, with a 60% sensitivity for acute interstitial rejection with or without vascular rejection and an 82% sensitivity for acute vascular rejection. Overall specificity was 95% and 96%, respectively. Early rejection was also accurately detected in three patients less than 48 hours following kidney transplantation. Duplex sonography has a useful role in evaluating posttransplantation renal failure. Abnormal study results may obviate the need for biopsy and help in guiding clinical management.
对24例接受肾移植的患者进行了69次双功超声检查。在对多普勒波形进行前瞻性定性分析后，将结果与活检材料以及每位患者的临床病程进行了关联。肾内动脉血流多普勒波形的搏动性增加表明检查结果异常，提示急性排斥反应。总体敏感性因排斥反应的组织学类型而异，急性间质性排斥反应（无论有无血管排斥）的敏感性为60%，急性血管排斥的敏感性为82%。总体特异性分别为95%和96%。在肾移植后不到48小时的3例患者中也准确检测到了早期排斥反应。双功超声在评估移植后肾衰竭方面具有重要作用。异常的检查结果可能无需进行活检，并有助于指导临床管理。
