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房间隔支架治疗左心房僵硬综合征

Interatrial Stent to Treat Stiff Left Atrium Syndrome.

作者信息

Zaidi Danish, Williams Derek, Zhao David, Upadhya Bharathi, Gilbert Olivia

机构信息

Department of Internal Medicine, Yale-New Haven Hospital, New Haven, CT, United States of America.

Section of Pediatric Cardiology, Department of Pediatrics, Wake Forest School of Medicine, Winston-Salem, NC, United States of America.

出版信息

Cardiovasc Revasc Med. 2022 Jul;40S:337-340. doi: 10.1016/j.carrev.2022.01.004. Epub 2022 Jan 11.

DOI:10.1016/j.carrev.2022.01.004
PMID:35105508
Abstract

BACKGROUND

Catheter ablation for atrial fibrillation (CAAF) can result in stiff left atrial syndrome (SLAS) in up to 8% of patients. SLAS can be challenging to diagnose and difficult to distinguish from heart failure with preserved ejection fraction (HFpEF), presenting with similar signs and symptoms.

CASE PRESENTATION

We report the first case of using an interatrial stent to maintain therapeutic benefit of atrial septostomy in a patient with symptomatic SLAS. While interatrial shunt devices have preliminarily been shown to be safe and efficacious for the treatment of HFpEF, their utilization in those with SLAS has not previously been described [1].

CONCLUSIONS

In patients with prior CAAF, SLAS should be considered to explain dyspnea when alternative processes have been excluded. Treatment of SLAS can be challenging with medical therapy alone, and septostomy may provide significant symptomatic benefit in these patients. Interatrial stenting can improve the patency of such interventions.

摘要

背景

心房颤动导管消融术(CAAF)在高达8%的患者中可导致左心房僵硬综合征(SLAS)。SLAS的诊断具有挑战性,且难以与射血分数保留的心力衰竭(HFpEF)相区分,二者具有相似的体征和症状。

病例报告

我们报告了首例在有症状的SLAS患者中使用房间隔支架来维持房间隔造口术治疗效果的病例。虽然房间隔分流装置已初步显示对HFpEF的治疗安全有效,但此前尚未描述其在SLAS患者中的应用[1]。

结论

在既往接受CAAF的患者中,当排除其他病因后,应考虑SLAS来解释呼吸困难。仅用药物治疗SLAS可能具有挑战性,房间隔造口术可能为这些患者带来显著的症状改善。房间隔支架置入可提高此类干预措施的通畅性。

相似文献

1
Interatrial Stent to Treat Stiff Left Atrium Syndrome.房间隔支架治疗左心房僵硬综合征
Cardiovasc Revasc Med. 2022 Jul;40S:337-340. doi: 10.1016/j.carrev.2022.01.004. Epub 2022 Jan 11.
2
Interatrial Shunt Devices.房间隔分流装置
Heart Fail Clin. 2024 Jan;20(1):61-69. doi: 10.1016/j.hfc.2023.05.003. Epub 2023 Jul 4.
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Transcatheter Interatrial Shunt Device for the Treatment of Heart Failure: Rationale and Design of the Randomized Trial to REDUCE Elevated Left Atrial Pressure in Heart Failure (REDUCE LAP-HF I).用于治疗心力衰竭的经导管房间隔分流装置:降低心力衰竭患者升高的左心房压力的随机试验(REDUCE LAP-HF I)的原理与设计
Circ Heart Fail. 2016 Jul;9(7). doi: 10.1161/CIRCHEARTFAILURE.116.003025.
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Impact of an interatrial shunt device on survival and heart failure hospitalization in patients with preserved ejection fraction.房间隔分流装置对射血分数保留心力衰竭患者生存和心力衰竭住院的影响。
ESC Heart Fail. 2019 Feb;6(1):62-69. doi: 10.1002/ehf2.12350. Epub 2018 Oct 11.
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Heart failure with preserved ejection fraction or non-cardiac dyspnea in paroxysmal atrial fibrillation: The role of left atrial strain.射血分数保留的心力衰竭或阵发性心房颤动中的非心源性呼吸困难:左心房应变的作用。
Int J Cardiol. 2021 Jan 15;323:161-167. doi: 10.1016/j.ijcard.2020.08.093. Epub 2020 Sep 1.
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Device-based percutaneous treatments to decompress the left atrium in heart failure with preserved ejection fraction.基于器械的经皮治疗以减轻射血分数保留的心力衰竭患者的左心房压力。
Heart Fail Rev. 2023 Mar;28(2):315-330. doi: 10.1007/s10741-022-10280-4. Epub 2022 Nov 19.
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Atrial Septostomy to Treat Stiff Left Atrium Syndrome.房间隔造口术治疗左房僵硬综合征
Circ Heart Fail. 2017 Jul;10(7). doi: 10.1161/CIRCHEARTFAILURE.117.004160.
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Double Transseptal Access for Atrial Fibrillation Ablation in the Presence of Investigational Interatrial Shunt Device.在存在试验性房间隔分流装置的情况下,用于心房颤动消融的双经房间隔入路
JACC Case Rep. 2020 Dec 23;3(1):136-140. doi: 10.1016/j.jaccas.2020.09.056. eCollection 2021 Jan.
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Rationale and Design of the Reduce Elevated Left Atrial Pressure in Patients With Heart Failure (Reduce LAP-HF) Trial.心力衰竭患者降低升高的左心房压力(Reduce LAP-HF)试验的原理与设计
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Interatrial shunt devices for the treatment of heart failure.房间隔分流装置治疗心力衰竭。
Trends Cardiovasc Med. 2021 Oct;31(7):427-432. doi: 10.1016/j.tcm.2020.09.004. Epub 2020 Oct 3.

引用本文的文献

1
Exploring the causes of stiff left atrial syndrome: a case series.探索左房僵硬综合征的病因:病例系列研究
Eur Heart J Case Rep. 2025 Jan 20;9(2):ytae702. doi: 10.1093/ehjcr/ytae702. eCollection 2025 Feb.
2
A case of severely progressive left atrial calcification triggered by inflammation due to radiofrequency catheter ablation.一例因射频导管消融炎症引发的严重进行性左心房钙化病例。
J Cardiol Cases. 2024 Jun 5;30(3):87-89. doi: 10.1016/j.jccase.2024.05.009. eCollection 2024 Sep.