大规模快速接种 SARS-CoV2 疫苗对关注变异株热点地区的影响。
Impacts of rapid mass vaccination against SARS-CoV2 in an early variant of concern hotspot.
机构信息
University of Salzburg, Department of Economics, Residenzplatz 9, A-5010, Salzburg, Austria.
Institute of Virology, Department of Hygiene, Microbiology and Public Health, Medical University of Innsbruck, Peter-Mayr-Str. 4b, 6020, Innsbruck, Austria.
出版信息
Nat Commun. 2022 Feb 1;13(1):612. doi: 10.1038/s41467-022-28233-8.
We study the real-life effect of an unprecedented rapid mass vaccination campaign. Following a large outbreak of the Beta variant in the district of Schwaz/Austria, 100,000 doses of BNT162b2 (Pfizer/BioNTech) were procured to mass vaccinate the entire adult population of the district between the 11th and 16th of March 2021. This made the district the first widely inoculated region in Europe. We examine the effect of this campaign on the number of infections, cases of variants of concern, hospital and ICU admissions. We compare Schwaz with (i) a control group of highly similar districts, and (ii) with populations residing in municipalities along the border of Schwaz which were just excluded from the campaign. We find large and significant decreases for all outcomes after the campaign. Our results suggest that rapid mass vaccination is an effective tool to curb the spread of SARS-CoV-2.
我们研究了一场史无前例的大规模疫苗接种运动在现实生活中的效果。在 Schwaz 区（奥地利）爆发 Beta 变体疫情后，我们采购了 10 万剂 BNT162b2（辉瑞/生物科技），以便在 2021 年 3 月 11 日至 16 日期间为该地区的所有成年人进行大规模接种。这使该地区成为欧洲第一个广泛接种疫苗的地区。我们研究了这场运动对感染人数、关注变体病例、住院和 ICU 入院人数的影响。我们将 Schwaz 与（i）高度相似的对照组地区，以及（ii）与 Schwaz 边境沿线居住的、刚好被排除在接种运动之外的城镇人口进行了比较。我们发现，接种运动后所有结果都有显著且大幅度的下降。我们的研究结果表明，快速大规模接种疫苗是遏制 SARS-CoV-2 传播的有效工具。
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